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Record W4413834951 · doi:10.3389/fonc.2025.1465104

Global research trends in radiotherapy for bone metastases: a systematic bibliometric analysis

2025· review· en· W4413834951 on OpenAlexaboutno aff
Fadong Yin, Xuan Liu, Xianxiu Nan, Xinjue Shi, Jing Yuan, Liu Qiteng, Yuyan Gao

Bibliographic record

VenueFrontiers in Oncology · 2025
Typereview
Languageen
FieldMedicine
TopicManagement of metastatic bone disease
Canadian institutionsnot available
Fundersnot available
KeywordsRadiation therapyMedicineBibliometricsSystematic reviewMedical physicsMEDLINEOncologyComputer scienceInternal medicineLibrary scienceBiology

Abstract

fetched live from OpenAlex

Background: With the development of various advanced radiotherapy techniques, research related to radiotherapy for bone metastases has made great progress, and scholars have published a large number of publications. In this study, we summarized the knowledge structure of radiotherapy for bone metastases and outlined the research hotspots through bibliometric analysis. Methods: Publications on radiotherapy for bone metastases from 1992 to 2024 were searched in the Web of Science Core Collection (WoSCC) database. Countries, institutions, authors, references, and keywords in the field were visualized using VOSviewer version 1.6.19 and CiteSpace version 6.3.R1. Results: 1303 publications from 71 countries were included in this study. The number of research publications on radiotherapy for bone metastases has been increasing year by year. The United States of America (USA) ranking first in terms of publication count and co-citation frequency. The most prolific institutions and authors were the University of Toronto and Sahgal A, while Chow E was the most co-cited author. The most co-cited paper was published by Lutz S et al. in 2011 in Internation Journal Of Radiation Oncology Physics. "stereotactic body radiotherapy", "spine metastases", "spinal cord compression", " immunotherapy" and "oligometastases" are the main keywords of the current research topics. Conclusions: The application of stereotactic body radiotherapy (SBRT) in the treatment of patients with bone metastases, especially oligometastases, has attracted extensive attention from researchers. How to choose reasonable radiotherapy for patients with complicated bone metastases has now become a research hotspot. Radiotherapy combined with immunotherapy may be the future development trend.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.019
metaresearch head score (Gemma)0.079
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Bibliometrics
Consensus categoriesnone
DomainCandidate signal: Evaluation · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.981
Threshold uncertainty score0.099

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0190.079
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0070.008
Bibliometrics0.1710.212
Science and technology studies0.0010.001
Scholarly communication0.0040.005
Open science0.0010.004
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.114
GPT teacher head0.509
Teacher spread0.396 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designMeta-analysis
DomainEvaluation
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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Same venueFrontiers in OncologySame topicManagement of metastatic bone diseaseFrench-language works237,207