MétaCan
Menu
Back to cohort
Record W4413838946 · doi:10.1101/2025.08.28.671991

′Candidatus Phytoplasma zeae′: community-driven delineation of the maize bushy stunt phytoplasma, a Dalbulus-transmitted corn pathogen confined to the Americas

2025· preprint· en· W4413838946 on OpenAlexafffund
Thierry Alexandre Pellegrinetti, Joshua Molligan, Abraão Almeida Santos, Maria Cristina Canale, Maíra Rodrigues Duffeck, Alejandro Olmedo-Velarde, Jordanne Jacques, Ivair Valmorbida, Ashleigh M. Faris, Marcos Vinícius Silva de Andrade, Magda Alana Pompeli Manica, Mauricio Luna, Paola Reyes-Caldas, Jairo Rodríguez Chalarca, Tim Dumonceaux, Edel Pérez‐López

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typepreprint
Languageen
FieldAgricultural and Biological Sciences
TopicPhytoplasmas and Hemiptera pathogens
Canadian institutionsSaskatoon City HospitalUniversité Laval
FundersNatural Sciences and Engineering Research Council of CanadaFonds de recherche du Québec – Nature et technologiesFundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina
KeywordsPhytoplasmaBiologyPathogenCandidatusVirologyBotanyPolymerase chain reactionMicrobiologyBacteriaGeneGeneticsRestriction fragment length polymorphism16S ribosomal RNA

Abstract

fetched live from OpenAlex

A novel phytoplasma species, ′Candidatus Phytoplasma zeae′, is proposed based on ecological distinctiveness, vector specificity, whole-genome comparisons, and community consensus. This phytoplasma is associated with maize bushy stunt (MBS) disease in corn (Zea mays) and is transmitted exclusively by Dalbulus maidis and D. elimatus, two leafhopper species endemic to the Americas. , and has been reported in Brazil, Colombia, Mexico, Peru, and several U.S. states. Here we sequenced and assembled the genome of MBS phytoplasma strains from Brazil, and U.S. to describe and propose this new species. Although the 16S rRNA gene sequence of the proposed reference strain, MBSP–BRRS, shares >99% identity with that of ′Ca. Phytoplasma asteris′, key nucleotide polymorphisms distinguish ′Ca. P. zeae′ from other 16SrI-related phytoplasma species. Average nucleotide identity (ANI) and average amino acid identity (AAI) values between ′Ca. P. zeae′ and ′Ca. P. asteris′ are 97.70–98.00% and 96.65–96.88%, respectively, both near the established species delineation thresholds. Comparative genomic analyses revealed unique gene clusters in ′Ca. P. zeae′ associated with amino acid transport, defence mechanisms, and protein turnover, which may contribute to its specialization in corn. The ecological profile of ′Ca. P. zeae′, including its narrow host range and restricted geographic distribution, supports its recognition as a novel species under Rule c of the IRPCM guidelines. The designation ′Candidatus Phytoplasma zeae′ is therefore proposed by members of the research community who have studied this pathogen for over a decade, with the MBSP-BrazilRS strain serving as the reference.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.686
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0020.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.219
Teacher spread0.201 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes2
Has abstractyes

Explore more

Same venuebioRxiv (Cold Spring Harbor Laboratory)Same topicPhytoplasmas and Hemiptera pathogensFrench-language works237,207