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Record W4413864914 · doi:10.1186/s13326-025-00335-4

A prototype ETL pipeline that uses HL7 FHIR RDF resources when deploying pure functions to enrich knowledge graph patient data

2025· article· en· W4413864914 on OpenAlexaff
Anusha Ansari, Marisa Conte, Allen Flynn

Bibliographic record

VenueJournal of Biomedical Semantics · 2025
Typearticle
Languageen
FieldComputer Science
TopicMachine Learning in Healthcare
Canadian institutionsCentre for Addiction and Mental Health
Fundersnot available
KeywordsComputer scienceRDFGraphPipeline (software)Knowledge graphInformation retrievalDatabaseLinked dataData scienceData miningProgramming languageTheoretical computer scienceSemantic Web

Abstract

fetched live from OpenAlex

BACKGROUND: For clinical care and research, knowledge graphs with patient data can be enriched by extracting parameters from a knowledge graph and then using them as inputs to compute new patient features with pure functions. Systematic and transparent methods for enriching knowledge graphs with newly computed patient features are of interest. When enriching the patient data in knowledge graphs this way, existing ontologies and well-known data resource standards can help promote semantic interoperability. RESULTS: We developed and tested a new data processing pipeline for extracting, computing, and returning newly computed results to a large knowledge graph populated with electronic health record and patient survey data. We show that RDF data resource types already specified by Health Level 7's FHIR RDF effort can be programmatically validated and then used by this new data processing pipeline to represent newly derived patient-level features. CONCLUSIONS: Knowledge graph technology can be augmented with standards-based semantic data processing pipelines for deploying and tracing the use of pure functions to derive new patient-level features from existing data. Semantic data processing pipelines enable research enterprises to report on new patient-level computations of interest with linked metadata that details the origin and background of every new computation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.012
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.018
Threshold uncertainty score0.062

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0060.012
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0020.001
Science and technology studies0.0010.001
Scholarly communication0.0030.005
Open science0.0020.003
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0180.007

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.331
Teacher spread0.289 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes1
Has abstractyes

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