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Record W4413871875 · doi:10.1177/21582440251372769

A Qualitative Evidence Synthesis of Women’s Experience of Infertility and Fertility Treatment From an Existential Perspective

2025· article· en· W4413871875 on OpenAlexaff
Andria Aiello, Mary Jane Esplen, Heather Boon, Rhonda Zwingerman, Brenda B. Toner, Robert Maunder

Bibliographic record

VenueSAGE Open · 2025
Typearticle
Languageen
FieldMedicine
TopicReproductive Health and Technologies
Canadian institutionsCReATe Fertility CentreOttawa Fertility CentreSinai Health SystemUniversity of Toronto
Fundersnot available
KeywordsInfertilityFertilityPerspective (graphical)ExistentialismQualitative researchGynecologyPsychologyFertility preservationPsychotherapistMedicineSociologyPregnancyPhilosophyEpistemologyBiologySocial sciencePopulationArt

Abstract

fetched live from OpenAlex

While infertility and fertility treatment cause significant psychological distress for many women, the effectiveness of existing psychological interventions is unproven. This paper explores the potential applicability of an existential psychotherapeutic framework in this context by reviewing the lived experience of women with infertility and women in fertility treatment from an existential perspective. We conducted a qualitative evidence synthesis, specifically a best fit framework synthesis. Qualitative studies that included quotations from women with infertility and women in fertility treatment addressing one or more existential concerns were reviewed. Irvin Yalom’s existential framework provided a pre-existing framework into which the findings from the studies were extracted and synthesized, producing a revised model. Of 1,506 studies screened, 144 satisfied inclusion criteria. Sixteen themes were populated deductively by quotations from the studies. Quotations not coded into the a priori themes were synthesized inductively to develop 13 additional themes, resulting in an Existential Model of Women in Fertility Treatment. Based on this model, the psychological challenges and opportunities for growth associated with infertility and fertility treatment can be understood as relating to: (1) loss and grief, and the threatened loss of symbolic immortality, (2) the powerlessness to direct one’s life, (3) alienation from the fertile world and diminished sense of self, and (4) the threatened loss of meaning and purpose. This review generated an Existential Model of Women in Fertility Treatment. Future research is needed to test the validity of this model, including research aimed at developing and testing existentially oriented interventions for this population.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.303
Threshold uncertainty score0.991

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.104
GPT teacher head0.484
Teacher spread0.381 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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