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Record W4413907043 · doi:10.14740/jocmr6315

Research on the Impact of Thyroid Disorders on Reproductive Function: A Narrative Review

2025· review· en· W4413907043 on OpenAlex
Jian Tan, Yang Yu, De Yin, Qun Xin, Xian Cai Ge

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueJournal of Clinical Medicine Research · 2025
Typereview
Languageen
FieldMedicine
TopicHuman Health and Disease
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineNarrative reviewThyroid functionThyroidNarrativeFunction (biology)Internal medicineIntensive care medicineEvolutionary biologyLinguisticsBiology

Abstract

fetched live from OpenAlex

Infertility, characterized by the failure to achieve clinical pregnancy after 12 months or more of regular unprotected sexual intercourse, has emerged as a substantial global reproductive health challenge. According to recent epidemiological studies, this condition affects approximately 15-20% of couples within the reproductive age group worldwide. Notably, thyroid dysfunction has been identified as a significant contributing factor, being present in 5-10% of infertile couples. Although the well-established association between thyroid dysfunction and human infertility has been extensively documented in the literature, the precise underlying mechanisms remain incompletely understood and continue to be a subject of ongoing scientific investigation. In this review, we comprehensively examine the current literature regarding the impact of abnormal thyroid function on reproductive health and explore potential therapeutic interventions for thyroid dysfunction-associated infertility. This analysis aims to identify promising research directions and advance treatment strategies for managing infertility related to thyroid disorders.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.086
metaresearch head score (Gemma)0.198
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.419
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0860.198
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0060.003
Bibliometrics0.0020.004
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.014
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.600
GPT teacher head0.717
Teacher spread0.118 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it