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Record W4413912101 · doi:10.1136/bmjopen-2024-094497

Establishing a framework of measurement for use in Long COVID research and practice: protocol for a scoping review involving evidence review and consultation

2025· review· en· W4413912101 on OpenAlexafffundabout
Kiera McDuff, Anne Bhéreur, Zeal Kadakia, Vicente Corrales‐Medina, Douglas P. Gross, Tania Janaudis‐Ferreira, Grace Y. Lam, Hiten Naik, Theone Paterson, Diana C. Sanchez‐Ramirez, Maxime Sasseville, Anisha Sekar, Sunita Vohra, Mark Bayley, Susan Birch, Jason W. Busse, Jill I. Cameron, Cara Kaup, Angela Cheung, Katie Churchill, Heather Edgell, Susie Goulding, Clayon B. Hamilton, Susan Jaglal, Pawan Kumar, Adeera Levin, Daniel Munblit, Florian Naye, Margaret O’Hara, James Plaismond, Jean-Marc Wilfried Supper, Kieran L. Quinn, Marina B. Wasilewski, Annette Wilkins, Kelly K. O’Brien

Bibliographic record

VenueBMJ Open · 2025
Typereview
Languageen
FieldMedicine
TopicLong-Term Effects of COVID-19
Canadian institutionsSunnybrook Health Science CentreOttawa HospitalBruyèrePublic Health OntarioMcMaster UniversityProvincial Health Services AuthorityUniversité de SherbrookeImpactTD Bank GroupToronto Rehabilitation InstituteUniversité LavalUniversity of ManitobaYork UniversityBaycrest HospitalSinai Health SystemUniversity of British ColumbiaUniversity of AlbertaUniversity Health NetworkWomen and Children’s Health Research InstituteUniversité de MontréalUniversity of VictoriaMcGill UniversityMcGill University Health CentreHealth Sciences CentreAlberta Health ServicesUniversity of Toronto
FundersTemerty Faculty of Medicine, University of TorontoCanada Research ChairsUniversity of TorontoMichael Smith Health Research BCPittsburgh Liver Research Center, University of PittsburghMcMaster University
KeywordsPsycINFOCINAHLMedicineMEDLINETerminologyGrey literatureScopusOutcome (game theory)Medical educationFamily medicineNursingPsychological intervention

Abstract

fetched live from OpenAlex

INTRODUCTION: Our aim is to develop a Framework of Measurement for people living with Long COVID and their caregivers for use in Long COVID research and clinical practice. Specifically, we will characterise evidence pertaining to outcome measurement and identify implementation considerations for use of outcome measures among adults and children living with Long COVID and their caregivers. METHODS AND ANALYSIS: We will conduct a scoping study involving: (1) an evidence review and (2) a two-phased consultation, using methodological steps outlined by the Arksey and O'Malley Framework and Joanna Briggs Institute. We will answer the following question: What is known about outcome measures used to describe, evaluate or predict health outcomes among adults and children living with Long COVID and their caregivers? EVIDENCE REVIEW: we will review peer review published and grey literature to identify existing outcome measures and their reported measurement properties with people living with Long COVID and their caregivers. We will search databases including MEDLINE, Embase, CINAHL, PsycINFO and Scopus for articles published since 2020. Two authors will independently review titles and abstracts, followed by full text to select articles that discuss or use outcome measures for Long COVID health outcomes, pertain to adults or children living with Long COVID and/or their caregivers and are based in research or clinical settings. We will extract data including article characteristics, terminology and definition of Long COVID, health outcomes assessed, characteristics of outcome measures, measurement properties and implementation considerations. We will collate and summarise data to establish a preliminary Framework of Measurement. Consultation phase 1: we will conduct an environmental scan involving a cross-sectional web-based questionnaire among individuals with experience using or completing outcome measures for Long COVID, to identify outcome measures not found in the evidence review and explore implementation considerations for outcome measurement in the context of Long COVID. Consultation phase 2: we will conduct focus groups to review the preliminary Framework of Measurement and to highlight implementation considerations for outcome measurement in Long COVID. We will analyse questionnaire and focus group data using descriptive and content analytical approaches. We will refine the Framework of Measurement based on the focus group consultation using community-engaged approaches with the research team. ETHICS AND DISSEMINATION: Protocol approved by the University of Toronto Health Sciences Research Ethics Board (protocol #46503) for the consultation phases of the study. Outcomes will include a Framework of Measurement, to enhance measurement of health outcomes in Long COVID research and clinical practice. Knowledge translation will also occur in the form of publications and presentations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.362
metaresearch head score (Gemma)0.324
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.362
Threshold uncertainty score0.787

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.3620.324
Meta-epidemiology (narrow)0.0080.009
Meta-epidemiology (broad)0.0150.022
Bibliometrics0.0270.027
Science and technology studies0.0100.012
Scholarly communication0.0180.022
Open science0.0120.019
Research integrity0.0220.017
Insufficient payload (model declined to judge)0.0620.023

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.600
GPT teacher head0.656
Teacher spread0.055 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designSystematic review
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes3
Has abstractyes

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