Feasibility and effectiveness of a handbook-based multidomain lifestyle intervention for older adults with mild cognitive impairment: A quasi-experimental design with propensity score matching
Bibliographic record
Abstract
Background The increasing prevalence of dementia highlights the urgent need for the social implementation of nonpharmacological interventions for its prevention. To address professional staff shortage challenges, we developed the MCI Handbook , a structured resource designed to guide non-professionals in promoting dementia prevention. Objective We aimed to evaluate the feasibility and effectiveness of MCI Handbook -based multidomain lifestyle interventions provided by nonprofessionals. Methods A 12-month intervention was implemented for older adults with mild cognitive impairment (MCI) recruited from two facilities in Japan. The feasibility outcomes included class participation rates and satisfaction with the intervention measured using the Japanese version of the 8-item client satisfaction questionnaire (CSQ-8J). Effectiveness was assessed based on changes in the Japanese version of the Montreal Cognitive Assessment (MoCA-J) scores. Results In total, 37 participants (16 males and 21 females; mean age, 78.6 years) were included. The mean class participation rate was 88.3 ± 17.7%, with high satisfaction reported by the participants (average CSQ-8J score, 25.6 ± 3.4). The MoCA-J score improved significantly from 21.9 ± 2.9 at baseline to 23.3 ± 3.8 at 12 months (p = 0.007), highlighting the clinical relevance of this intervention. Compared with the external control group, the intervention group showed significantly greater cognitive improvements (p = 0.017). Conclusions These findings demonstrate the feasibility and effectiveness of a 12-month multidomain lifestyle intervention conducted by nonprofessionals using the MCI Handbook . This program offers a promising, resource-efficient approach to dementia prevention. Future studies are needed to refine the delivery strategies and explore scalable methods for the broader implementation of multidomain interventions for dementia prevention.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.022 | 0.014 |
| Meta-epidemiology (narrow) | 0.002 | 0.001 |
| Meta-epidemiology (broad) | 0.003 | 0.003 |
| Bibliometrics | 0.002 | 0.001 |
| Science and technology studies | 0.001 | 0.002 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.003 | 0.001 |
| Insufficient payload (model declined to judge) | 0.005 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".