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Record W4413932872 · doi:10.1111/anae.16751

Point‐of‐care ultrasound of the upper airway in difficult airway management: a systematic review and meta‐analysis*

2025· review· en· W4413932872 on OpenAlexaff
Vedish Soni, Ameya Pappu, Sahar Zarabi, Carlos Khalil, Kong Eric You-Ten, Naveed Siddiqui, David T. Wong, Vincent Chan, Qixuan Li, Ella Huzsti, Marina Englesakis, Mandeep Singh

Bibliographic record

VenueAnaesthesia · 2025
Typereview
Languageen
FieldMedicine
TopicAirway Management and Intubation Techniques
Canadian institutionsUniversity of TorontoUniversity Health NetworkUniversity of British ColumbiaToronto Western HospitalWomen's College HospitalMcMaster University
Fundersnot available
KeywordsMedicineEpiglottisMeta-analysisReceiver operating characteristicAirwayLaryngoscopyIntubationArea under the curveAirway managementObservational studySystematic reviewLarynxUltrasoundRadiologyMEDLINEInternal medicineSurgery

Abstract

fetched live from OpenAlex

INTRODUCTION: The utility of bedside screening tests for the prediction of difficult airways is limited. There is growing interest in the role of point-of-care-ultrasound in airway assessment and management. This systematic review and meta-analysis aimed to determine the diagnostic utility and clinical application of various upper airway point-of-care-ultrasound parameters in the prediction of difficult airways. METHODS: We searched databases for randomised controlled trials, observational studies and case series with more than five cases. RESULTS: In total, 60 studies involving 10,580 patients, evaluating 58 parameters were included. For difficult facemask ventilation, a narrative synthesis showed that increased tongue thickness was associated with an increased incidence of a difficult airway. For prediction of difficult laryngoscopy, the sensitivity, specificity and area under the receiver operator characteristic curve (AUROC) for distance from-skin-to-vocal-cords were 0.84 (95%CI 0.74-0.91), 0.81 (95%CI 0.61-0.92) and 0.87 (95%CI 0.78-0.89), respectively (high certainty of evidence). For prediction of difficult tracheal intubation, distance from skin-to-epiglottis had the highest sensitivity (0.80 (95%CI 0.74-0.85)) and specificity (0.86 (95%CI 0.74-0.91)) (high certainty of evidence), while distance from skin-to-hyoid had the highest AUROC of 0.86 (95% CI 0.73-0.92), with a sensitivity and specificity of 0.78 (95%CI 0.60-0.89) and 0.81 (95%CI 0.63-0.91), respectively (moderate certainty of evidence). Ultrasound use was associated with higher first pass success in percutaneous tracheostomy (odds ratio (95%CI) 3.9 (2.1-71), (low-moderate certainty of evidence)) and improved cricothyroid membrane identification compared with palpation (odds ratio (95%CI) 3.61 (2.20-5.92) (moderate-high certainty of evidence)). DISCUSSION: Upper airway point-of-care ultrasound may improve prediction of difficult airways; its use is associated with improved first pass success in percutaneous tracheostomy. Future research should focus on evaluating its use in combination with a focused history and standard bedside examination tests, and in at-risk patient populations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.016
metaresearch head score (Gemma)0.050
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.016
Threshold uncertainty score0.084

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0160.050
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0150.027
Bibliometrics0.0050.006
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0020.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.305
Teacher spread0.287 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations15
Published2025
Admission routes1
Has abstractyes

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