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Record W4413943167 · doi:10.1097/sla.0000000000006928

Association of Neighborhood Socioeconomic Status and Ethnic Diversity with Failure to Rescue in Curative-intent Colorectal Cancer Surgery

2025· article· en· W4413943167 on OpenAlexaff
Adom Bondzi‐Simpson, Tiago Ribeiro, Andrea Covelli, Aïsha Lofters, Rinku Sutradhar, Rebecca A. Snyder, Callisia N. Clarke, Natalie G. Coburn, Julie Hallet

Bibliographic record

VenueAnnals of Surgery · 2025
Typearticle
Languageen
FieldMedicine
TopicGlobal Cancer Incidence and Screening
Canadian institutionsHealth Sciences CentreSunnybrook Health Science CentreSinai Health SystemWomen's College HospitalUniversity of Toronto
Fundersnot available
KeywordsMedicineSocioeconomic statusOdds ratioDemographyConfidence intervalEthnic groupLogistic regressionColorectal cancerConfoundingPopulationRetrospective cohort studyCancerInternal medicineGerontologyEnvironmental health

Abstract

fetched live from OpenAlex

OBJECTIVE: To examine the association between neighborhood-level socioeconomic status (SES) and ethnic diversity and failure to rescue (FTR) after curative-intent colorectal cancer (CRC) resection. BACKGROUND OF DATA: FTR is an outcome reflecting a system's ability to detect and treat clinical deterioration after complications. However, little is known about how social characteristics influence FTR in oncologic populations. METHODS: We conducted a population-based retrospective cohort study of adults undergoing resection for stage I-III CRC (2007-2020). Exposures were SES and ethnic diversity defined by ecologic measures from census data. The primary outcome was FTR, defined as in-hospital death following a major postoperative complication. Logistic regression examined the association between exposures and FTR while adjusting for confounders. Subgroup analysis explored associations by cancer site and procedure setting. RESULTS: Among 60,470 patients included, FTR occurred in 1,158 (1.9%). Of those, 25.0% resided in the lowest SES neighborhood (5th quintile) versus 16.9% in the highest (1st quintile) (P<0.001), and 18.5% resided in the most ethnically diverse neighborhoods (5th quintile) versus 21.2% in the least (1st quintile, P=0.12). After adjustment, residing in the lowest SES (Odds Ratio, OR 1.26; 95% confidence interval, CI 1.05-1.52) or most ethnically diverse neighborhoods (OR 1.53, 95%CI 1.26-1.85) was associated with higher odds of FTR compared to patients residing in the highest SES or least ethnically diverse neighborhoods. These observations persisted in the colon but not rectal cancer subgroup and in the emergency but not elective setting. CONCLUSION: These findings outline inequalities in post-operative outcomes by social characteristics pointing towards potential gaps in structures of care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.206
GPT teacher head0.375
Teacher spread0.169 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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