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Record W4413999783 · doi:10.1155/ijm/9956724

Multidrug‐Resistant Virulent <i>Escherichia coli</i> Strains in Cattle: Implications on Food Safety and Public Health

2025· article· en· W4413999783 on OpenAlexaff
Ajay Kumar, Emmanuel W. Bumunang, Peter Kotsoana Montso, Collins Njie Ateba

Bibliographic record

VenueInternational Journal of Microbiology · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicEscherichia coli research studies
Canadian institutionsUniversity of Lethbridge
FundersNorth-West University
KeywordsVirulenceMultiple drug resistanceEscherichia coliFood safetyMicrobiologyPublic healthVeterinary medicineMedicineEnvironmental healthBiologyDrug resistanceGeneFood scienceGeneticsNursing

Abstract

fetched live from OpenAlex

Escherichia coli inhabit the gastrointestinal tract of mammals, including cattle, where they occur as commensals. However, some strains have evolved as highly virulent pathogens that also harbor a variety of multidrug‐resistant determinants. In the present study, from cattle fecal samples, a total of 636 confirmed E. coli strains were obtained based on the presence of the uidA housekeeping gene. Of the seven antibiotics tested, 120 isolates displayed multiple antibiotic‐resistant (MAR) traits, with two strains (ERO138 and EKL68) showing resistance to six antibiotics. The hlyA (62.5%) was the most prevalent among the MAR isolates. In addition, 11 (9.1%) isolates harbored all four screened virulence genes ( eaeA , stx1 , stx2 , and hlyA ). Seven of the 120 MAR isolates displayed moderate biofilm‐producing properties, and two of these isolates (ERO157 and EKL127) harbored all four virulence genes tested. Pulsed field gel electrophoresis (PFGE) analysis revealed that all 120 MAR isolates clustered into eight groups, displaying high genetic variability. These findings are important for screening and monitoring of diverse E. coli isolates from cattle in the Northwest region of South that harbors virulence and multiple antibiotic resistance traits.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.006
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.314
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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