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Record W4414002630 · doi:10.1249/mss.0000000000003847

Motor Unit Discharge Rates During Maximal Fatiguing Eccentric Contractions and Recovery in the Human Elbow Extensors

2025· article· en· W4414002630 on OpenAlexaff
Daniel C. Basile, Charles L. Rice

Bibliographic record

VenueMedicine & Science in Sports & Exercise · 2025
Typearticle
Languageen
FieldEngineering
TopicMuscle activation and electromyography studies
Canadian institutionsWestern University
Fundersnot available
KeywordsEccentricIsometric exerciseMotor unitConcentricElbowPhysical medicine and rehabilitationMuscle fatigueMedicineCardiologyElectromyographyPhysical therapyAnatomyMathematicsPhysics

Abstract

fetched live from OpenAlex

INTRODUCTION: Eccentric (ECC) contractions are uniquely characterized by higher maximal torque output compared with concentric or isometric actions. However, this advantage is accompanied by greater and more prolonged torque loss following fatiguing ECC exercise compared with other modalities. Although muscle contractile responses to dynamic fatiguing contractions have been documented, the neural control of ECC contractions-particularly at the level of individual motor units-remains poorly understood. The purpose was to evaluate motor unit discharge rate (MUDR) modulation during and in recovery after a maximal effort ECC fatiguing task. METHODS: Single motor unit activity was recorded with fine-wire electrodes inserted into the triceps brachii muscle. Participants completed an elbow extension protocol with subsequent recovery for 30 min, involving repetitive sets of 10 maximal repetitions until 50% torque loss relative to baseline maximal ECC torque. RESULTS: MUDR declined substantially (>35%) from baseline to task failure (37.1 vs 23.1 Hz, P ≤ 0.001) and did not return to baseline values until 10 min of recovery ( P = 0.597). However, both electrically stimulated twitch torque and maximal voluntary ECC torque remained depressed at 30 min ( P = 0.001), relative to baseline. CONCLUSIONS: This study provides a novel characterization of motor unit behavior during fatigue induced by maximal ECC contractions, revealing a significant reduction consistent with prior evidence of impaired MUDR under other fatiguing tasks. In addition, results indicate that prolonged torque depression (30 min post-task failure) following the ECC fatiguing task is primarily attributable to peripheral muscle impairments, as MUDR recovered to baseline within ~10 min.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.263
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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