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Record W4414026607 · doi:10.1080/17434440.2025.2557403

Post-operative infection with a single-use ureteroscope with real-time intrarenal pressure monitoring vs. all other single-use ureteroscopes

2025· article· en· W4414026607 on OpenAlexaff
Naeem Bhojani, Kathryn Morris, John White, Sirikan Rojanasarot, Emma Tran, Manoj Monga

Bibliographic record

VenueExpert Review of Medical Devices · 2025
Typearticle
Languageen
FieldMedicine
TopicKidney Stones and Urolithiasis Treatments
Canadian institutionsUniversité de Montréal
FundersBoston Scientific Corporation
KeywordsURETEROSCOPEMedicineSingle useUreteroscopySingle CenterUrologyInternal medicineSurgeryUreter

Abstract

fetched live from OpenAlex

Background Evidence for LithoVue™ Elite Single-Use Digital Flexible Ureteroscope (LVE) with pressure monitoring vs. other single-use ureteroscopes is needed.Research Design and Methods This study using US electronic health records evaluated patients undergoing ureteroscopy (URS) with laser lithotripsy between 1 January 2023-1 June 2025. The primary endpoint was post-operative infection, defined as urinary tract infection, sepsis, and other infections, assessed at 10- and 30-days post-index procedure. Propensity score matching controlled for baseline differences.Results After matching, 208 patients with LVE with pressure monitoring (mean age 61.4; 48.1% female; 85.1% White) and 416 with other single-use ureteroscopes without pressure monitoring (mean age 61.8; 48.4% female; 85.1% White) were evaluated. Post-operative LVE with pressure monitoring infection was significantly lower 30-days post-index (8.2% vs. 15.4%; p = 0.016). Multivariable analyses confirmed significantly higher odds of 30-day infection with other single-use ureteroscopes (odds ratio 2.17 [95% confidence interval 1.21-4.10]; p = 0.012). Post-operative sepsis and other infections did not statistically differ; however, post-operative 30-day UTI was significantly less with LVE with pressure monitoring (5.2% vs. 10.8%; p = 0.033).Conclusions LVE with pressure monitoring was associated with reduced 30-day post-URS infection. These findings support clinical improvement associated with LVE and suggest intrarenal pressure monitoring may contribute to better short-term outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.655
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.341
Teacher spread0.319 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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