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Record W4414048012 · doi:10.1016/j.ibreh.2025.100045

Preventive, personalized, and precision medicine and biomarkers for breast cancer diagnosis: Artificial intelligence framework

2025· article· en· W4414048012 on OpenAlexaff
Udita J. Monani, Suchismita Das, Sanjay Saxena, Gavino Faa, Manudeep Kalra, John R. Laird, Mustafa Al-Maini, Inder M. Singh, Laura E. Mantella, Narendra N. Khanna, Rajesh Kumar Singh, Vijay Singh Rathore, Ekta Tiwari, Amer M. Johri, Mostafa M. Fouda, Esma R. Isenović, Mario Scartozzi, Pankaj K. Jain, Luca Saba, Jasjit S. Suri

Bibliographic record

VenueInnovative Practice in Breast Health · 2025
Typearticle
Languageen
FieldMedicine
TopicRadiomics and Machine Learning in Medical Imaging
Canadian institutionsQueen's UniversityUniversity of Toronto
Fundersnot available
KeywordsPrecision medicineBreast cancerPersonalized medicineProfiling (computer programming)Lobular carcinomaApplications of artificial intelligenceMammographyInvasive lobular carcinoma

Abstract

fetched live from OpenAlex

• AI models improve diagnostic accuracy in breast cancer imaging tasks (AUC >0.95). • Molecular profiling advances personalized treatment regimens. • DL algorithms show promise but require ethical oversight and prospective validation. Personalized medicine is needed since standard breast cancer diagnosis and treatment are not always exact or customized. To revolutionize breast cancer diagnosis, this paper examines the clinical utility of artificial intelligence (AI), specifically deep learning (DL). The accuracy with which AI can analyze vast medical databases—genetic data, clinical background, and images— enabling improved accuracy in diagnosis, staging, and treatment planning through integration of multimodal data. Recent studies have shown that DL algorithms have already attained 94–98 % diagnostic accuracies in recognizing breast cancer subtypes from histopathological images, against the overall accuracy of approximately 88 % of an average human pathologist. Additionally, CNNs have achieved AUC values of >0.95 in distinguishing between malignant and benign breast lesions based on mammography, substantiating the fact that AI enhances the diagnostic accuracy with a significant improvement. The study highlights a few case studies, such as fibroadenoma, invasive lobular carcinoma (ILC), lobular carcinoma in situ (LCIS), and sclerosing adenosis (SAD), to illustrate how DL algorithms outperform human experts in early detection and correct diagnosis. Incorporating DL into personalized medicine not only guarantees more specialized and effective treatment plans but also guarantees a future where every patient with breast cancer will be treated with personalized care. Other than referencing AI's revolutionizing impact on breast cancer screening, this research offers an unassailable case for adopting AI and signals a new epoch of accurate, patient-centered medicine.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.006
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.003
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.434
Teacher spread0.402 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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