Optimizing Laser Therapy: Efficacy and Safety of Picosecond 1,064 nm Nd:YAG Laser in Xanthelasma Palpebrarum Treatment
Bibliographic record
Abstract
Background: Xanthelasma palpebrarum (XP) currently lacks a universally endorsed treatment approach. The utility of picosecond 1064 nm Nd:YAG lasers in XP management has not been explored. Objective: This study aimed to assess the efficacy and safety of picosecond 1064 nm Nd:YAG laser therapy in the treatment of XP. Methods: A total of 47 patients with clinically confirmed XP received treatment with picosecond 1064 nm Nd:YAG laser at standardized settings. Patients were photographed using standardized photographic documentation, and the degree of clearance was evaluated. Results: Following the initial treatment session, 97.87% of patients exhibited a good response to the picosecond laser, with some degree of lesion clearance. By the third session, 78.80% of patients achieved > 50% lesion clearance. Adverse effects were mild and transient, with postinflammatory hyperpigmentation observed in 2 (4.25%) patients. Conclusion: The picosecond 1064 nm Nd:YAG laser demonstrated promising efficacy in the treatment of XP, with a potentially enhanced safety profile.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".