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Record W4414083890

Tongue lesions in feedlot cattle associated with ergot alkaloid consumption.

2025· article· en· W4414083890 on OpenAlexaffabout
Meghan Brookhart, Greg Dimmers, Dayna Goldsmith, Eugene Janzen, Vanessa Cowan, Felipe Reggeti, Francisco A. Uzal, Timothy W. J. Olchowy, Beverly J. Morrison, Erin Zachar, John Remnant, Lindsay Rogers, Katie Waine

Bibliographic record

VenuePubMed · 2025
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicPlant and fungal interactions
Canadian institutionsUniversity of Saskatchewan
Fundersnot available
KeywordsFeedlotOutbreakTongueHolstein CattleMycotoxinAnimal husbandryEtiology
DOInot available

Abstract

fetched live from OpenAlex

Over 1200 heavy feedlot cattle presented with severe tongue lesions during a 7-month interval. Review of the literature and discussions with colleagues revealed previous similar outbreaks had occurred in Canada and the USA, with extensive investigations conducted and no cause identified. In the current outbreak, examination of the environment, feed, water, cattle behavior, and husbandry systems were conducted, as well as diagnostic testing including necropsy, histopathology, bacteriology, virology, and toxicology. All the initial testing to determine the cause of the lesions was unrewarding. As cases continued and increased during the second month, a further inspection of feedstuffs was undertaken. Hard clumps were identified in the dried distiller's grains with solubles feed additive (DDGS), and samples were submitted for additional mycotoxin analysis. Toxic concentrations of ergot alkaloids were detected, leading to a presumptive diagnosis of localised ergot toxicosis. Removal of the affected DDGS from the diet led to a decrease and eventual cessation of cases. This case report highlights the value of extensive collaborations among onsite and offsite colleagues when conducting detailed investigations on farm of a diagnostically challenging case. Key clinical message: This report describes a large outbreak of tongue lesions in feedlot cattle associated with ergot toxicosis. The report highlights the extensive investigation with collaboration among the producer, veterinarians, laboratory teams, and colleagues from further afield. Toxic concentrations of ergot alkaloids were present in hard clumps in the dried distiller's grains with solubles feed additive (DDGS), suggesting a possible etiology of localized ergot toxicosis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.008
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.034
GPT teacher head0.219
Teacher spread0.185 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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