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Revealing Principal Components, Patterns, and Structural Gaps in Health Security among High-Income Countries: A Comparative Analysis Using PCA and a Multi-Scenario Clustering Approach

2025· preprint· en· W4414128145 on OpenAlexaff
Adel A. Nasser, Mijahed Nasser Aljober, Abed Saif Alghawli, Amani A. K. Essayed

Bibliographic record

VenueF1000Research · 2025
Typepreprint
Languageen
FieldMedicine
TopicViral Infections and Outbreaks Research
Canadian institutionsArtificial Intelligence in Medicine (Canada)
FundersDeanship of Scientific Research, Prince Sattam bin Abdulaziz UniversityPrince Sattam bin Abdulaziz University
KeywordsResilience (materials science)Principal (computer security)Principal component analysisCluster analysisOpen peer reviewOpen data

Abstract

fetched live from OpenAlex

Objectives: The COVID-19 pandemic highlighted significant weaknesses in health security systems, even in high-income countries (HICs), underscoring the necessity for a more nuanced understanding of their distinct strengths and vulnerabilities. Existing research often offers broad evaluations and fails to capture the complex internal dynamics of health-security performance. This study seeks to fill this gap by identifying the latent factors that define health security capacities in HICs and clustering countries based on these factors. Methods: A multistage analytical framework was employed based on the 2017-2021 Global Health Security Index (GHSI) dataset. Initially, Principal Component Analysis (PCA) with varimax rotation was applied to the 37 GHSI indicators to reduce dimensionality and reveal latent structures within the data. This process identified nine principal components for the subsequent analysis. Subsequently, K-means clustering was utilized under three methodological scenarios: using countries' average scores across the nine extracted components, based on 13 high-loading indicators from the first principal component, and using aggregated scores across the six original GHSI categories. This design facilitated a comprehensive comparison of the clustering outcomes across different data representations. Results: Analysis found nine components that together explained 74.50% of the total differences, with the first component-"Foundational Capacity, Regulations, Resilience, and Prevention-Detection Systems"-making up 37.62% of that total. Together, the first three components explained 51.81% of the total variance. Clustering across all three scenarios categorized high-income countries into four levels, revealing significant disparities. Nauru, the Cook Islands, and Palau consistently ranked lowest, highlighting critical gaps in foundational capacities and systemic readiness despite their high-income status. This study shows that wealth alone does not ensure preparedness, revealing distinct performance patterns and weaknesses across countries. Conclusion: The findings underscore the need for tailored policies, multi-method evaluations, and sustained global cooperation to enhance resilience and guide investments in national and global health security.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.539
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0020.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.003
Research integrity0.0000.003
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.084
GPT teacher head0.415
Teacher spread0.331 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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