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Record W4414161290 · doi:10.1080/01616412.2025.2559308

Factors associated with prolonged intensive unit stay following mechanical thrombectomy for acute ischemic stroke

2025· article· en· W4414161290 on OpenAlex
Saqib Chaudhry, Aysha Jadran, Hamza Khan, Zarina Laleka, Sairah Bashir, Pouya Tahsili Fahadan, Laith Altaweel, Ashfaq Shuaib, Adnan I. Qureshi

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueNeurological Research · 2025
Typearticle
Languageen
FieldMedicine
TopicAcute Ischemic Stroke Management
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsIntensive care unitStroke (engine)Ischemic strokeAcute strokeThrombolysis

Abstract

fetched live from OpenAlex

Objective and background The aim of the study was to investigate factors affecting the length of stay (LoS) in the intensive care unit (ICU) following mechanical thrombectomy (MT) for acute ischemic stroke.Methods We conducted a retrospective analysis using data from a prospective stroke registry at a comprehensive stroke center between January 2019 and June 2024. ICU stay for more than 48 hours was defined as prolonged ICU stay.Results Out of 808 patients, 39.2% (n = 317) required a prolonged ICU LoS. Prolonged ICU stay was more likely to have a baseline National Institutes of Health Stroke Scale NIHSS ≥ 15, higher mean HbA1c levels, posterior circulation stroke, intubation for the procedure, symptomatic intracerebral hemorrhage, in-patient mortality and ICU complications including pneumonia, deep vein thrombosis, pulmonary embolism, urinary tract infection (all p value < 0.05). Patients receiving thrombolysis prior to thrombectomy were less likely to have a prolonged LoS (p = 0.0025). Independent predictors for prolonged ICU LoS included baseline NIHSS ≥ 15 (odds ratio [OR] 1.83, p = 0.0004), intubation prior to the procedure (OR 2.20, p < 0.0001), receiving IV thrombolysis (OR 0.66, p = 0.0144), recanalization (OR 0.48, p = 0.0085, composite ICU complications (OR 2.66, p < 0.0001), and symptomatic intracranial hemorrhage (sICH) (OR 3.38, p < 0.0001).Conclusions Almost one-third of the acute ischemic stroke patients required a prolonged LoS following MT. A better understanding of the factors associated with prolonged ICU stay may assist in appropriate allocation of resources.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.009
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.162
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.009
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.001
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.156
GPT teacher head0.419
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it