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Record W4414161448 · doi:10.1109/tmi.2025.3609319

MultiASNet: Multimodal Label Noise Robust Framework for the Classification of Aortic Stenosis in Echocardiography

2025· article· en· W4414161448 on OpenAlexafffund
Andrea Fung, Bahar Khodabakhshian, Hooman Vaseli, Jamie Alexis Goco, Michael Tsang, Christina Luong, Purang Abolmaesumi, Teresa S.M. Tsang

Bibliographic record

VenueIEEE Transactions on Medical Imaging · 2025
Typearticle
Languageen
FieldMedicine
TopicPhonocardiography and Auscultation Techniques
Canadian institutionsUniversity of British Columbia
FundersNatural Sciences and Engineering Research Council of CanadaCanadian Institutes of Health Research
KeywordsNoise (video)InferenceDoppler effectDoppler ultrasoundClassifier (UML)Pattern recognition (psychology)StenosisCardiac imaging

Abstract

fetched live from OpenAlex

Aortic stenosis (AS), a prevalent and serious heart valve disorder, requires early detection but remains difficult to diagnose in routine practice. Although echocardiography with Doppler imaging is the clinical standard, these assessments are typically limited to trained specialists. Point-of-care ultrasound (POCUS) offers an accessible alternative for AS screening but is restricted to basic 2D B-mode imaging, often lacking the analysis Doppler provides. Our project introduces MultiASNet, a multimodal machine learning framework designed to enhance AS screening with POCUS by combining 2D B-mode videos with structured data from echocardiography reports, including Doppler parameters. Using contrastive learning, MultiASNet aligns video features with report features in tabular form from the same patient to improve interpretive quality. To address misalignment where a single report corresponds to multiple video views, some irrelevant to AS diagnosis, we use cross-attention in a transformer-based video and tabular network to assign less importance to irrelevant report data. The model integrates structured data only during training, enabling independent use with B-mode videos during inference for broader accessibility. MultiASNet also incorporates sample selection to counteract label noise from observer variability, yielding improved accuracy on two datasets. We achieved balanced accuracy scores of 93.0% on a private dataset and 83.9% on the public TMED-2 dataset for AS detection. For severity classification, balanced accuracy scores were 80.4% and 59.4% on the private and public datasets, respectively. This model facilitates reliable AS screening in non-specialist settings, bridging the gap left by Doppler data while reducing noise-related errors. Our code is publicly available at github.com/DeepRCL/MultiASNet.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.018
Threshold uncertainty score0.035

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.005
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0020.001
Science and technology studies0.0010.001
Scholarly communication0.0010.002
Open science0.0030.002
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0020.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.326
Teacher spread0.301 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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