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Record W4414188712 · doi:10.1101/2025.09.09.675155

<i>marApp</i> : An R package and web portal to calculate mutations- and genetic diversity-area relationship for conservation

2025· preprint· en· W4414188712 on OpenAlexaboutno aff
Meixi Lin, Kristy S. Mualim, Oliver Selmoni, Moisés Expósito‐Alonso

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2025
Typepreprint
Languageen
FieldEnvironmental Science
TopicSpecies Distribution and Climate Change
Canadian institutionsnot available
FundersBiological and Environmental ResearchCenter for Computational, Evolutionary and Human Genomics, Stanford UniversityCarnegie Institution of WashingtonU.S. Department of EnergyNational Institutes of HealthNational Science Foundation
KeywordsGenetic diversityConservation geneticsBiodiversityDiversity (politics)LimitingHabitat

Abstract

fetched live from OpenAlex

Abstract International conservation policies including the Kunming-Montreal Global Biodiversity Framework now consider genetic diversity of wild species in their targets. However, scalable, theory-driven tools to assess and predict genetic diversity loss are still emerging, limiting their use in conservation planning. Analogous to the species-area relationship, recent work has shown that genetic diversity scales with area, described by the mutations–area relationship (MAR) or genetic–diversity–area relationship (GDAR), can approximate the genetic diversity loss in a species from habitat reduction. To enable application of these insights for conservation practitioners and policy makers, we present the mar R package and marApp web portal, a fast and user-friendly tool for MAR/GDAR analysis. The mar package connects genetic diversity patterns in space to ecological theory, and automates steps from reading genetic and geographic data to simulating various habitat extinction scenarios using MAR/GDAR. The mar package estimates only short-term genetic diversity, providing a lower-limit for the far greater long-term genetic losses, underscoring the need to maximize present-day habitat conservation before it becomes irreversible. As a case example, we showcase predictions of coral ( Acropora sp.) genetic diversity loss from reef coverage impacts. We demonstrate the usage of marApp without requirements for prior genetics or coding experiences, and provide downloadable reports for conservation.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.005
metaresearch head score (Gemma)0.023
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Software · Consensus signal: Software
Teacher disagreement score0.136
Threshold uncertainty score0.456

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0050.023
Meta-epidemiology (narrow)0.0040.003
Meta-epidemiology (broad)0.0020.003
Bibliometrics0.0040.002
Science and technology studies0.0010.001
Scholarly communication0.0030.003
Open science0.0040.004
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.1360.079

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.030
GPT teacher head0.234
Teacher spread0.205 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreSoftware

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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