Cross-Cultural Consortium on Irritability (C3I): An International Network for Research on Cultural Similarities and Differences in Irritability
Bibliographic record
Abstract
Irritability is among the top reasons for youth mental health referrals worldwide. Cultural factors may affect how irritability manifests and develops; how it is experienced by youth and responded to by their caregivers; and how it is treated. However, the influences of cultural context on irritability have received little systematic investigation. The Cross-Cultural Consortium on Irritability (C3I; https://m.yale.edu/c3i ) is an international research network created to increase the limited evidence base on cross-cultural similarities and differences in irritability. By bringing together researchers worldwide, C3I provides an innovative and collaborative approach to address unmet needs and to explore novel research questions regarding cultural variation in irritability. In addition, combining resources and data around the globe helps to produce robust, reproducible, and generalizable results using large mega-data. One important initiative involves pooling existing datasets to support manuscript collaborations. The first 3 such projects focus on cross-cultural comparisons of the following irritability-related topics: boundaries of normative behavior; association with suicidality and self-harm; and informant effects. Another ongoing effort involves conceptualization of irritability across cultures. Other efforts include promoting projects of primary data collection using qualitative and quantitative methods, harmonization across measures, and facilitating/supporting community-based participatory research and engagement. C3I is an innovative, collaborative research structure to build a robust, reproducible, and generalizable evidence base on irritability and its characteristics, including sociocultural influences. This evidence base will facilitate recognition and assessment of irritability and, ultimately, inform development of effective, culturally informed prevention and intervention to benefit the largest possible number of youth and their families. This article describes the Cross-Cultural Consortium on Irritability (C3I), an international network aimed at understanding how culture shapes the presentation, experience, response to, and treatment of irritability in youth. By exploring these cultural influences, C3I seeks to improve recognition, assessment, and development of effective, culturally sensitive prevention and intervention strategies to benefit the largest possible number of youth and their families worldwide.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.004 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".