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Physiological Strain In Older Adults During A Simulated Extreme Heat Event: A Case Study

2025· article· en· W4414241980 on OpenAlexaffabout
Jennifer S. Peel, Sarah M. Taggart, Gil Bourgois, Kelli E. King, James J. McCormick, Glen P. Kenny

Bibliographic record

VenueMedicine & Science in Sports & Exercise · 2025
Typearticle
Languageen
FieldMedicine
TopicThermoregulation and physiological responses
Canadian institutionsUniversity of Ottawa
Fundersnot available
KeywordsCore temperatureDaytimeThermoregulationRelative humidityCore (optical fiber)Heat waveExtreme heatHeart rateExtreme Cold

Abstract

fetched live from OpenAlex

The likelihood of exposure to hot indoor environments is increasing as climate change exacerbates the frequency and severity of extreme heat events. Recent work from our laboratory demonstrated that older adults sustain greater increases in core temperature during a daylong (9-h) exposure to hot indoor conditions (40 °C) compared to their younger counterparts (PMID:37707866). While these findings represent an important step in quantifying the physiological effects of heat waves on heat-vulnerable individuals, there remains a need for extended studies performed over multiple days, as would occur in a natural heat event. PURPOSE: To evaluate the thermal and cardiovascular responses to a multi-day heatwave simulation in an older adult. METHODS: A 60-year-old male was housed in an environmental chamber for three successive days while exposed to a daytime temperature of 40 °C (45% relative humidity [RH]) for a 10-h period (9:00-19:00) and a nighttime temperature of 36 °C (45% RH) for a 14-h period (19:00-9:00). The participant was permitted to move freely throughout the day but not perform physical activity. A battery of tests assessing cardiovascular and cognitive function, and postural stability were performed in the final 2-h of daytime. Core temperature (rectal; Trec) and heart rate (HR) were measured prior to entry to the heat (ambient temperature; 22 °C) and continuously throughout the trial. RESULTS: Pre-trial resting Trec was 36.5 °C. Prior to the battery of tests (8-h into daytime exposure) Trec reached 37.5 °C, 37.8 °C and 37.5 °C and further increased by 0.2 °C, 0 °C and 0.3 °C at the end of daytime exposure (10-h) for days 1, 2 and 3 respectively. Nighttime was associated with a reduction in Trec, with end nighttime Trec decreasing to 36.9 °C (day 1), 37.0 °C (day 2) and 37.1 °C (day 3). Pre-trial HR was 46 beats per min (bpm), which increased to 66 bpm, 65 bpm, 59 bpm at 8-h, with a further increase of 7 bpm, 12 bpm and 9 bpm at end of daytime (10-h) and a decrease to 48 bpm, 48 bpm, 55 bpm at the end of nighttime for day 1 to 3 respectively. CONCLUSION: We showed that a multi-day exposure to extreme heat is associated with a sustained increase in physiological strain. Notably, the marked elevation in daytime Trec occurred despite a reduction in nighttime temperature closer to resting levels. Supported by: Health Canada HeatADAPT program

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0010.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.337
Teacher spread0.306 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2025
Admission routes2
Has abstractyes

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