MétaCan
Menu
Back to cohort
Record W4414258633 · doi:10.1177/17470161251346253

Rethinking ethical reflexivity and oversight in health research through an ecosystem approach: A workshop report

2025· article· en· W4414258633 on OpenAlexaff
Katharine Wright, Joseph Ali, Caesar Atuire, Phaik Yeong Cheah, Anna Chiumento, Agata Ferretti, Adrienne Hunt, Sharon Kaur, Rachel L Knowles, Carleigh Krubiner, Florencia Luna, Paul Ndebele, Ana Palmero, James Shaw, Effy Vayena, Teck Chuan Voo, Jantina de Vries, Katherine Littler

Bibliographic record

VenueResearch Ethics · 2025
Typearticle
Languageen
FieldMedicine
TopicEthics in Clinical Research
Canadian institutionsUniversity of Toronto
FundersFogarty International CenterMedical Research CouncilSouth African Medical Research CouncilNational Institutes of HealthUK Research and InnovationWellcome Trust
KeywordsResearch ethicsReflexivityScrutinyAccountabilityAgency (philosophy)BioethicsContext (archaeology)General partnershipScope (computer science)

Abstract

fetched live from OpenAlex

As the scope of morally relevant considerations widens and new challenges emerge at the frontiers of health innovation, there are questions about the appropriate role and remit for research ethics review, within the broader context of the whole health research ecosystem. Drawing on discussion at a satellite meeting at the 2022 Global Forum on Bioethics in Research in Cape Town, we argue that the ethical conduct of research is the responsibility of all stakeholders in the research ecosystem – from funders, governments and research institutions to individual research teams and ethics committees. As a research community we need to espouse, and take action to achieve, more distributed approaches to ethical scrutiny and reflexivity. A crucial element of such a shift should be the development of collaborative and non-adversarial relationships between researchers and ethics committees that recognise and respect the mutual responsibilities of all parties to promote ethical research conduct. In tandem with the development of systems to support the exercise of ethical responsibilities across the research ecosystem, committees need to reconceptualise their role, in partnership with communities, as one of providing accountability through a focus on how research promotes participant agency and the common good.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.219
metaresearch head score (Gemma)0.104
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.781
Threshold uncertainty score0.963

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2190.104
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.002
Bibliometrics0.0010.001
Science and technology studies0.0110.019
Scholarly communication0.0240.021
Open science0.0060.033
Research integrity0.0170.027
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.922
GPT teacher head0.746
Teacher spread0.176 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designQualitative
DomainMethods
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venueResearch EthicsSame topicEthics in Clinical ResearchFrench-language works237,207