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Record W4414273415 · doi:10.1016/s1474-4422(25)00304-7

2024 MAGNIMS–CMSC–NAIMS consensus recommendations on the use of MRI for the diagnosis of multiple sclerosis

2025· review· en· W4414273415 on OpenAlexafffund
Frederik Barkhof, Daniel S. Reich, Jiwon Oh, Maria A. Rocca, David K.B. Li, Pascal Sati, Christina Azevedo, Francesca Bagnato, Peter A. Calabresi, Olga Ciccarelli, Michael G. Dwyer, Gabriele C. DeLuca, Nicola De Stefano, Christian Enzinger, Massimo Filippi, Cristina Granziera, June Halper, Roland G. Henry, Claudio Gasperini, Susan A. Gauthier, Ludwig Kappos, Cornelia Laule, Scott D. Newsome, Xavier Montalbán, Sarah A. Morrow, Menno M. Schoonheim, Nancy L. Sicotte, Ahmed Toosy, Jeffrey Wilken, Tarek Yousry, Jaume Sastre‐Garriga, Anthony Traboulsee, Daniel Ontaneda, Àlex Rovira

Bibliographic record

VenueThe Lancet Neurology · 2025
Typereview
Languageen
FieldMedicine
TopicMultiple Sclerosis Research Studies
Canadian institutionsUniversity of British ColumbiaUniversity of TorontoUniversity of CalgaryInternational Collaboration On Repair DiscoveriesSt. Michael's Hospital
FundersInstituto de Salud Carlos IIIEMD SeronoAstraZenecaGenentechMultiple Sclerosis SocietySchweizerische Multiple Sklerose GesellschaftJanssen PharmaceuticalsSanofi GenzymeNovo NordiskMedDay PharmaceuticalsMinistero della SaluteCelgeneAmsterdam NeuroscienceRosetrees TrustIdorsia PharmaceuticalsZonMwNational Institute for Health and Care ResearchNational Research FoundationShionogiAlexion PharmaceuticalsMyelin Repair FoundationWellcome TrustKiniksa PharmaceuticalsAtara BiotherapeuticsNational Institutes of HealthInternational Collaboration on Repair DiscoveriesMylanSanofiTG TherapeuticsEuropean Committee for Treatment and Research in Multiple SclerosisEurostarsPatient-Centered Outcomes Research InstituteMedical Research CouncilNational Health and Medical Research CouncilNeuraxpharmCraig H. Neilsen FoundationBristol-Myers SquibbTeva Pharmaceutical IndustriesFondazione Italiana Sclerosi MultiplaNatural Sciences and Engineering Research Council of CanadaPfizerBiogenEli Lilly and CompanyU.S. Department of DefenseMultiple Sclerosis International FederationCSL BehringSamsungAllerganMultiple Sclerosis Society of CanadaRace to Erase MSU.S. Department of Health and Human Services
KeywordsMultiple sclerosisMagnetic resonance imagingClinical PracticeMcDonald criteriaSpinal cordMedical imaging

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.011
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.459
Threshold uncertainty score0.997

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.011
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.481
GPT teacher head0.423
Teacher spread0.057 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations61
Published2025
Admission routes2
Has abstractno

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