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Record W4414358161 · doi:10.1038/s41893-025-01634-5

Mapping meta-analyses on organochlorine pesticides reveals low methodological quality

2025· article· en· W4414358161 on OpenAlexaff
Kyle Morrison, Yefeng Yang, Coralie Williams, Lorenzo Ricolfi, Malgorzata Lagisz, Shinichi Nakagawa

Bibliographic record

VenueNature Sustainability · 2025
Typearticle
Languageen
FieldDecision Sciences
Topicscientometrics and bibliometrics research
Canadian institutionsUniversity of Alberta
FundersUniversity of New South Wales
KeywordsQuality (philosophy)Organochlorine pesticideEnvironmental qualityWildlifeQuality assessment

Abstract

fetched live from OpenAlex

Abstract Rachel Carson’s Silent Spring inspired a wave of research on the impacts of organochlorine pesticides, followed by a subsequent wave of meta-analyses. However, the methodological quality and content of these meta-analyses has not been evaluated. Here we systematically map and evaluate the methodological quality of 105 meta-analyses on organochlorine pesticides. We found that 83.4% of the evaluated methodological elements are low quality using the Collaboration for Environmental Evidence Synthesis Assessment Tool (CEESAT v2.1). We then reveal that 227 policy documents cited the included meta-analyses, and there is no difference in methodological quality between those that were cited in policy and those that were not. We also found a paucity of meta-analyses on wildlife despite ample primary evidence. Finally, we quantified the positive impact of using reporting guidelines and we provide recommendations for readily implementable methodological improvements.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.382
metaresearch head score (Gemma)0.777
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Meta-epidemiology (broad), Bibliometrics
Consensus categoriesMetaresearch
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.994
Threshold uncertainty score0.762

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.3820.777
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0060.013
Bibliometrics0.0270.033
Science and technology studies0.0020.004
Scholarly communication0.0140.006
Open science0.0040.008
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0040.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.834
GPT teacher head0.710
Teacher spread0.124 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; the direct Gemma label and the distilled Codex classifier agree on what is shown here.

Study designSystematic review
DomainMethods
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2025
Admission routes1
Has abstractyes

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