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Record W4414378541 · doi:10.1093/europace/euaf196

Epicardial and hybrid surgical ablation of atrial fibrillation: 1-year follow-up outcomes of the EORP EHAFA registry

2025· article· en· W4414378541 on OpenAlexfundno aff
Mindy Vroomen, Kai-Nicolas Doll, Thierry Folliguet, Carina Blomström Lundqvist, Lluı́s Mont, Nicholas S. Peters, Laurent Pison, Rodrigo Ferrari, Ángeles Alonso, Jeroen J. Bax, C. Blomström‐Lundqvist, Stephan Gielen, Patrizio Lancellotti, A P Maggioni, Fausto J. Pinto, Frank Ruschitzka, L Tavazzi, P Vardas, Franz Weidinger, Uwe Zeymer, Alec Vahanian, A Budaj, N. Dagres, Nicolas Danchin, Victoria Delgado, Jonathan Emberson, Örjan Friberg, Gr. Heyndrickx, Stefan James, A. Pieter Kappetein, G Parati, A-S Petronio, Mikko Pietilä, Eva Prescott, Frans Van de Werf, B. Beleslin, Ovidiu Chioncel, David Erlinge, M Glikson, Alastair Gray, А. О. Недошивин, A-P Petronio, J W Roos-Hesselink, Lars Wallentin, B A Popescu, David Adlam, Alida L.P. Caforio, D Capodanno, Marc R. Dweck, J. Hausleiter, Peter Ludman, Lars H. Lund, С.Т. Мацкеплишвили, Benjamin Meder, Danilo Neglia, Agnès Pasquet, Fernando J. Rossello, Sameh Shaheen, Aleksandra Torbica, Mark La Meir, Aleš Mokráček, Nicolas Doll, Aldo P. Maggioni, Ines Van Loo, Ruaa Al‐Qazazi, Rajiv Tanwani, Brigita Zile, Sohaib Haseeb, Alan Bulava, Petr Pařízek, Luděk Haman, Marek Pojar, Petr Budera, Pavel Osmančík, David Peñalver Talavera, Radka Procházková, Dalibor Heřman, Josef Kautzner, Jan Pirk, Dan Wichterle, Bashar Aldhoon, Petr Kačer, Robert Čihák, Petr Peichl, A Polednova, Philippe Chevalier, Jacques Robin, Jean-Francois Obaida, Carine Flys, Bertrand Marcheix, H Mondor, Éric Bergoend, Etienne Grunenwald, Anne Rollin, Issam Abouliatim, Stéphane Combes, Malte Kuniss, Ersan Akkaya, Christine Scheld, Volkmar Falk, Christoph Starck, Alexander Meyer, Matthias Bauer, Jaime‐Jürgen Eulert‐Grehn, Sabine Huebler, Mahmoud Wehbe, Giuseppe Cittadini, Audrius Aidietis, Vilius Janušauskas, Niels Verberkmoes, Pepijn van der Voort, Jurren M. van Opstal, Jan Van Es, R G H Speekenbrink, Tamara Tap-Smeele, Wendy Breukers, Dirk Jan van Veldhuisen, Massimo A. Mariani, Yuri Blaauw, Reinder C Steenbergen, J. H. H. Deuling, Bao‐Oanh Nguyen, Meelad I H Al-Jazairi, Suzanne Philippens, Rypko Beukema, Reinder Evertz, Sjoerd Westra, Leen van Garsse, Ad J.J.C. Bogers, Natasja de Groot, A Muskens, Jacek Bednarek, Jerzy Sadowski, Piotr Suwalski, Sebastian Stec, Dariusz A. Kosior, Anna Witkowska, Espen Fengsrud, Johan Probst, Jürg Gruenenfelder, Sacha P. Salzberg, Tom Wong, Shouvik Haldar, Anthony DeSouza, Toufan Bahrami, John Pepper, Vennela Boyalla, Habib Khan, Ines Kralj‐Hans

Bibliographic record

VenueEP Europace · 2025
Typearticle
Languageen
FieldMedicine
TopicAtrial Fibrillation Management and Outcomes
Canadian institutionsnot available
FundersAbbott VascularBristol-Myers Squibb CanadaDaiichi Sankyo EuropeBayerServierUppsala UniversitetAkademiska SjukhusetNovartis PharmaMaastricht Universitair Medisch CentrumVrije Universiteit BrusselAmgenBoehringer IngelheimRadboud UniversiteitPfizerFakultní nemocnice Hradec KrálovéResMedBoston Scientific CorporationUniversitair Medisch Centrum GroningenFoundation for Cardiovascular ResearchEli Lilly and CompanyBristol-Myers SquibbAstraZenecaAtriCureSanofiGedeon RichterUniversiteit MaastrichtEdwards Lifesciences
KeywordsAblationComplicationAtrial fibrillationCatheter ablationSinus rhythm

Abstract

fetched live from OpenAlex

AIMS: Stand-alone minimal invasive epicardial and hybrid atrial fibrillation ablation (EHAFA) has evolved to a recognized treatment option in challenging patients. The EHAFA registry was initiated to describe the applied diagnostic and therapeutic approaches used in routine practice for these procedures, as well as the outcomes in terms of rhythm, symptoms, and complications. METHODS AND RESULTS: Between January 2016 and March 2018, patients who underwent an EHAFA procedure for all types of atrial fibrillation (AF) were consecutively enrolled in the international, prospective, observational EHAFA registry. Follow-up occurred after 1 year. A total of 468 patients were enrolled from 17 centres in 10 countries. Stand-alone ablation (n = 464) was performed epicardially in 47% (n = 220) or as epi-/endocardial hybrid in 53% (n = 244). The predominate type of AF was non-paroxysmal in 74% (n = 342), and 36% (n = 166) of patients had failed previous catheter ablation. The main lesion sets applied consisted of pulmonary vein isolation (99%, n = 460) and isolation of the left atrial (LA) posterior wall (82%, n = 383). In 82% (n = 382), the LA appendage was managed. The overall in-hospital major complication rate was 8.2% (n = 38/464). Freedom from atrial arrhythmias > 30 s with and without antiarrhythmic drug usage was 79% and 64% (n = 279/353, n = 223/351, respectively). The EHRA score at follow-up was clearly reduced compared to preoperatively (EHRA I: 72%, n = 233/325, vs. 3%, n = 14/464). CONCLUSION: This international registry revealed good rhythm control efficacy for epicardial and hybrid AF ablation in patients with advanced AF, leading to improvement in AF-related symptoms. However, a certain associated complication rate needs to be considered.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.130
Threshold uncertainty score0.314

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.306
Teacher spread0.280 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations1
Published2025
Admission routes1
Has abstractyes

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