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Record W4414399034 · doi:10.1139/apnm-2025-0112

Cardiorespiratory response to high-intensity interval exercise across the menstrual cycle and with oral contraceptive use in recreationally active females

2025· article· en· W4414399034 on OpenAlexvenueno aff
Alyssa Olenick, Regis C. Pearson, Nathan T. Jenkins

Bibliographic record

VenueApplied Physiology Nutrition and Metabolism · 2025
Typearticle
Languageen
FieldMedicine
TopicSports Performance and Training
Canadian institutionsnot available
FundersUniversity of Georgia
KeywordsCardiorespiratory fitnessLuteal phaseMenstrual cycleFollicular phaseHeart ratePopulationMenstruationCycle ergometer

Abstract

fetched live from OpenAlex

Fluctuations in female sex hormones may influence the cardiorespiratory response to exercise. Cardiorespiratory response to high-intensity interval exercise (HIIE) across the menstrual cycle (MC) or with oral contraceptive (OC) use has limited data. Therefore, the influence of MC phase and OC use on cardiorespiratory response during HIIE was assessed. Twenty-five females (24.4 (3.6) years) were categorized by a natural MC (non-oral contraceptive users (NOC), n = 14) or OC use ( n = 11). HIIE was four sets of four repetitions with 3 min rest between intervals on a cycle ergometer at a power output halfway between the ventilatory threshold and V̇O 2peak. An HIIE bout was performed during the early follicular and mid-luteal phases (days 2–7 and ∼21 of the MC) and during inactive (days 2–7) and active pill (third week) phases. Cardiorespiratory responses to HIIE were assessed via indirect calorimetry. No group or cycle phase differences were noted for relative and absolute VO 2 , ventilatory exchange, heart rate, or rating of perceived exertion ( p > 0.05). In NOC during the follicular phase, FEO 2 and V̇E/V̇O 2 during pre-exercise seated rest was lower compared to the luteal phase ( p < 0.05). In NOC during the follicular phase, V̇E/CO 2 , FEO 2 , FECO 2, V̇E/V̇O 2 , and V̇E/CO 2 during warmup was lower compared to the luteal phase ( p < 0.05). Most cardiorespiratory variables assessed do not appear to be impacted by MC phase or OC use during HIIE.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.285
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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