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Record W4414422545 · doi:10.1155/jt/6365547

Sublethal Effects of Cameroon Field‐Used Pesticides on Growth and Organ Health in <i>Archachatina marginata</i>

2025· article· en· W4414422545 on OpenAlex
Annick N. Enangue Njembele, Sylvie C Ntyam Epse Ondo, Kingsley Agbor Etchu

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

fundA Canadian funder is recorded on the work.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueJournal of Toxicology · 2025
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicPesticide Exposure and Toxicity
Canadian institutionsnot available
FundersUniversité Laval
KeywordsCypermethrinPesticideMetalaxylGlyphosateToxicityKidneyEcotoxicologyPesticide residue

Abstract

fetched live from OpenAlex

Cameroon rainforest region is not only an agricultural area with massive pesticide uses but also possesses factors that favor land snails’ growth like Archachatina marginata . The present study aimed to assess the impact of sub‐chronic exposure of commonly used pesticides in Cameroon, glyphosate, metalaxyl, and cypermethrin on the growth, survival, histological structure of key organs, and tissue residue levels in Archachatina marginata . Therefore, sub‐adult (under 30 g) Archachatina marginata snails were exposed for 10 weeks, once a week to field‐relevant concentrations of glyphosate (0.5 g/L), metalaxyl (3.3 g/L), and cypermethrin (2 g/L), while the control group was exposed with tap water. The experiment was repeated four times. Survival and body weight were recorded weekly. Post exposure, tissue residues were analyzed by GC‐MS, and histological examinations of the kidney and ovo‐testis (snails’ gonad) were performed. The result showed no significant differences in the survival or external morphology of exposed snails. However, deeper statistical analyses revealed that snails exposed to metalaxyl had significantly lower final weights compared to all other groups with a mean loss of −8.7 g (−26.6%). A histological examination revealed visible alteration in the kidney and ovo‐testis tissues of treated snails, though these changes could not be confirmed statistically. Moreover, pesticide residues were detected in the tissues of treated animals, with trace amounts of glyphosate and cypermethrin also found in control snails, likely due to prior contamination or cross‐cage drift. In conclusion, sub‐chronic exposure to field‐used pesticides did not induce mortality in Archachatina marginata but did affect growth and tissue integrity, especially under metalaxyl exposure. These findings raise concerns about sub‐lethal toxicity and food safety risks and support the use of Archachatina marginata as a bioindicator in pesticide‐exposed environments.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.638
Threshold uncertainty score0.164

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.251
Teacher spread0.243 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it