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Record W4414428268 · doi:10.1177/12034754251368849

A Canadian Consensus on Androgenetic Alopecia: Approach and Management

2025· article· en· W4414428268 on OpenAlexaffabout
Ian Landells, Eunice Y. Chow, Aditya K. Gupta, Julio C. Jasso-Olivares, Thusanth Thuraisingam, Renita Ahluwalia, Jerry Tan, M.E. Pratt, Geeta Yadav, Quinton Chivers, Tristan Laforest, Elias Raad, Jayden Owen, Nour R. Dayeh

Bibliographic record

VenueJournal of Cutaneous Medicine and Surgery · 2025
Typearticle
Languageen
FieldMedicine
TopicHair Growth and Disorders
Canadian institutionsMontreal Clinical Research InstituteMemorial University of NewfoundlandWindsor Clinical ResearchCanadian Heart Research CentreUniversity of OttawaMediprobe Research (Canada)University of TorontoIron Ore Company (Canada)Hôpital Maisonneuve-RosemontUniversity of AlbertaNexus Clinical Research (Canada)
Fundersnot available
KeywordsPsychological interventionShampooLotionAffect (linguistics)Hair lossRandomized controlled trialIntense pulsed lightPharmacovigilance

Abstract

fetched live from OpenAlex

Androgenetic alopecia (AGA) is the most common hair loss condition affecting between 40% to 50% of Canadian men and women by 50 years of age. This nonscarring hereditary condition can significantly affect patients, impacting their overall well-being and quality of life. Despite the multitude of interventions and the willingness of people with AGA to try treatments, there are no clear Canadian guidelines on its management. An expert panel of 11 physicians developed Delphi-based consensus recommendations of interventions for the management of AGA in male and female adults. Forty-five interventions were reviewed. Seven interventions are recommended, including oral dutasteride; oral finasteride; topical finasteride; topical minoxidil; platelet-rich plasma; microneedling; and oral minoxidil. Five interventions are recommended with near consensus: intralesional dutasteride; ketoconazole shampoo; low level laser therapy; aminexil; as part of a regimen and 17 are not recommended (adenosine; cetirizine; carboxytherapy; amla syrup; microfilament thread; Nourkrin; injectable minoxidil; caffeine; ceramide; topical herbal formulations; piroctone olamine shampoo or leave-on; rosemary oil; shampoo and lotion hair care products containing fermented papaya, fermented mangosteen, and caffeine; basic Fibroblast Growth Factor (bFGF); flutamide).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.266
Threshold uncertainty score0.352

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.249
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes2
Has abstractyes

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