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Record W4414461914 · doi:10.2196/71854

Effect of Physiotherapy Intervention on Improvement of Respiratory Function and Degree of Respiratory Distress Reduction in Neonates With Respiratory Distress Syndrome: Protocol for a Systematic Review

2025· review· en· W4414461914 on OpenAlexvenueno aff
Sharath Hullumani, Moh’d Irshad Qureshi, Raghumahanti Raghuveer, Sakshi Desai, Neha A Brahmane, Pratiksha Warghat

Bibliographic record

VenueJMIR Research Protocols · 2025
Typereview
Languageen
FieldMedicine
TopicNeonatal Respiratory Health Research
Canadian institutionsnot available
Fundersnot available
KeywordsIntervention (counseling)Protocol (science)Respiratory distressRespiratory systemNeonatal respiratory distress syndromeDistressClinical PracticeRandomized controlled trial

Abstract

fetched live from OpenAlex

Background: Neonatal respiratory distress syndrome (NRDS), a common and serious illness in preterm infants, is characterized by lung immaturity and inadequate surfactant production. Even though improvements in neonatal care have increased survival rates, optimizing supportive therapies such as physiotherapy is still essential to improve respiratory outcomes and overall recovery. Objective: This study aims to evaluate the effectiveness of physiotherapy therapies in enhancing respiratory function and clinical outcomes in neonates with NRDS. Methods: PRISMA-P (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols) guidelines will be followed for conducting a systematic review. Studies assessing the effects of physiotherapy therapies on newborns with NRDS, such as respiratory exercises, manual chest compressions, percussion, vibration, and postural drainage, high-frequency oscillation of the chest wall, cough stimulation, or suctioning will be included. A comprehensive search of electronic databases, including PubMed, Embase, CINAHL, and the Cochrane Library, to find pertinent observational studies, experimental studies, and randomized controlled trials, will be conducted. Important outcomes will be respiratory function metrics, oxygen saturation levels, length of mechanical ventilation, occurrence of problems, and overall newborn outcomes. Results: Exact numbers are not accessible at this time, as the review is hypothetical and has not yet been conducted. In order to inform clinical procedures and future studies, the results will contain data on respiratory improvement, intervention kinds, safety profiles, and the best times and frequencies for physical therapy in neonates with respiratory distress syndrome. Conclusions: This review will provide a comprehensive understanding of the role of physiotherapy in managing NRDS and its impact on clinical outcomes in neonates. The findings may guide clinical practice and inform future research on noninvasive strategies for improving neonatal respiratory care.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.042
metaresearch head score (Gemma)0.053
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Protocol · Consensus signal: Protocol
Teacher disagreement score0.049
Threshold uncertainty score0.224

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0420.053
Meta-epidemiology (narrow)0.0060.004
Meta-epidemiology (broad)0.0240.028
Bibliometrics0.0090.010
Science and technology studies0.0040.004
Scholarly communication0.0070.008
Open science0.0050.005
Research integrity0.0070.006
Insufficient payload (model declined to judge)0.0490.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.211
GPT teacher head0.591
Teacher spread0.380 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreProtocol

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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