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Record W4414485414 · doi:10.5501/wjv.v14.i3.111071

Study characteristics on health-related quality of life in older people living with human immunodeficiency virus: A narrative review

2025· review· en· W4414485414 on OpenAlexaff
Phan Sok, Mary V. Seeman, Sean B. Rourke

Bibliographic record

VenueWorld Journal of Virology · 2025
Typereview
Languageen
FieldMedicine
TopicHIV-related health complications and treatments
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsNarrative reviewOlder peopleContext (archaeology)NarrativeHuman immunodeficiency virus (HIV)Quality of life (healthcare)

Abstract

fetched live from OpenAlex

BACKGROUND People living with human immunodeficiency virus (HIV) are aging as a result the benefits of combination antiretroviral therapy. AIM To provide descriptions of eligible existing studies on demographics, methodologies, and outcome measures related to health-related quality of life (HRQoL) in the context of HIV and aging. METHODS The MEDLINE, CINAHL, Scopus, and PsycINFO databases were systematically searched using the terms HIV, age, and HRQoL to find studies published between January 1995 and June 2022. Key variables of the eligible studies were identified and categorized into demographics (e.g. , study sites, study year), methodologies (e.g. , use of conceptual frameworks, measures used), and outcome measures [e.g. , HRQoL, quality of life (QoL)]. The PRISMA 2009 checklist was followed. RESULTS A total of 68 published studies involving 53504 participants were included. The majority of the studies (55.88%) were conducted in North America, with relatively few studies conducted in Africa. The median age of participants was 51.0 years (IQR = 11.0). Over one-third (32.56%) of all participants were older people living with HIV aged 50 years and older Four studies included only older female participants, and six studies included only men who have sex with men. Outcome measures were assessed as HRQoL (26.47%) or QoL (36.76%). Overall, data from African studies, older women living with HIV, socioeconomic status (e.g. , employment, income, education), sexual behavioral risks, theoretical frameworks used, and follow-up studies were limited. CONCLUSION This narrative review highlights imbalances and gaps in research on HRQoL in the context of HIV and aging, providing direction for future studies in this area.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.494
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0060.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.061
GPT teacher head0.430
Teacher spread0.369 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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