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Record W4414491550 · doi:10.1097/psy.0000000000001439

The Grieving Heart: The Association Between Hemodynamic Responses to Grief Recall and Prolonged Grief Disorder Symptoms

2025· article· en· W4414491550 on OpenAlexaff
Vincent Goldberg, Mary‐Frances O'Connor, Roman Palitsky, Harald Gündel, Marc N. Jarczok

Bibliographic record

VenueBiopsychosocial Science and Medicine · 2025
Typearticle
Languageen
FieldPsychology
TopicGrief, Bereavement, and Mental Health
Canadian institutionsArtificial Intelligence in Medicine (Canada)
Fundersnot available
KeywordsHemodynamicsGriefRecallAssociation (psychology)Haemodynamic responseTask (project management)

Abstract

fetched live from OpenAlex

OBJECTIVE: The death of a loved one is among the most stressful life events. Across cultures, grief is associated with increased morbidity and mortality. In addition to psychological distress, grieving includes physical components, such as elevated blood pressure (BP). This study investigated hemodynamic responses to a grief-related interview and the impact of grief severity on cardiovascular reactivity in bereaved individuals 6 to 24 months post-loss. METHODS: Sixty-seven participants (85% females, aged 60 ± 6 years) underwent BP measurements during baseline, after a 5 to 10-minute grief recall task (GR), and during a 10-minute recovery period. Repeated measures ANOVAs compared systolic (SBP) and diastolic BP (DBP) at baseline and 0, 5, and 10 minutes post-GR. ANOVAs were controlled for age, sex, time since loss, and antihypertensive medication. Pairwise comparisons between time points were calculated. Participants meeting prolonged grief disorder (PGD) criteria ( n = 6) were descriptively compared with individuals reporting grief severity below the median ( n = 32) of the Prolonged Grief-13 questionnaire and to those above the median without PGD ( n = 29). RESULTS: SBP and DBP increased post-GR and remained elevated during the 10-minute recovery [SBP: F(3, 186) = 3.950, p = .009, η 2 p = 0.060; DBP: F(3, 186) = 1.923, p = .13, η 2 p = 0.030]. Pairwise comparisons revealed significant differences between SBP and DBP at baseline compared with post-GR measurements. Descriptively, the PGD subgroup showed higher baseline values, similarly pronounced reactivity compared with the rest of the sample (contrary to previous findings), and a delayed decline in SBP and DBP, particularly compared with participants with low grief severity. CONCLUSIONS: Findings support the hypothesis that higher PGD symptoms may be linked to a dysregulated hemodynamic stress response. Furthermore, results suggest that the GR is a feasible, transcultural task for eliciting grief-related hemodynamic responses in bereaved individuals up to 2 years post-loss.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.173
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0020.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.365
Teacher spread0.348 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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