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Record W4414529664 · doi:10.1111/vcp.70048

<i>Cryptococcus gattii</i> Infection in the Carpal Joint of a Goat

2025· article· en· W4414529664 on OpenAlexaff
Sarah N. Bosch, Peres Ramos Badial, Heather A. Roe, Oscar Alas, Hayley Paradise, Airtor Gallastegui, Diego De Gasperi, Ian K. Hawkins, Aline Rodrigues Hoffmann, Christopher J. Lanier, Tara P. Arndt

Bibliographic record

VenueVeterinary Clinical Pathology · 2025
Typearticle
Languageen
FieldMedicine
TopicFungal Infections and Studies
Canadian institutionsAltasciences (Canada)
Fundersnot available
KeywordsHistopathologyCarpal JointCryptococcusCytologyLamenessDirect agglutination test

Abstract

fetched live from OpenAlex

A 5-year-old LaMancha goat buck presented for evaluation of a 1-week history of progressive lameness and carpal swelling in the left thoracic limb. Cytology performed on an aspirate from the left radiocarpal joint identified abundant round to oval, thickly encapsulated, extracellular yeast organisms that occasionally exhibited narrow-based budding, features compatible with Cryptococcus spp. yeast. The patient was euthanized due to poor prognosis, and a necropsy was performed. Histopathology confirmed the presence of numerous fungal yeast associated with the left radiocarpal joint. A cryptococcal serum latex agglutination test was negative. However, panfungal PCR and fungal culture identified the organisms as Cryptococcus gattii. This report describes, for the first time, a case of a C. gattii infection affecting the joint of a goat.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.017
Threshold uncertainty score0.259

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.123
GPT teacher head0.434
Teacher spread0.311 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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