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Exploring the Role of Wideband Tympanometry in Diagnosis of Meniere’s Disease: A Systematic Review and Meta-analysis

2025· article· en· W4414540383 on OpenAlexaboutno aff
Alireza Sharifi, Hamed Sajjadi, Sahar Ghaedsharaf, Varasteh Vakili Zarch, Khashayar Ashkboos, Amin Soroushan, Mohammad R. Pourmousa, Mohammad Ebrahim Ghaffari, Ali Kouhi

Bibliographic record

VenueIndian Journal of Otology · 2025
Typearticle
Languageen
FieldNeuroscience
TopicVestibular and auditory disorders
Canadian institutionsnot available
Fundersnot available
KeywordsTympanometryInclusion and exclusion criteriaDiseaseMEDLINEMeta-analysisControl (management)

Abstract

fetched live from OpenAlex

Objective: We aimed to investigate the diagnostic role of wideband tympanometry (WBT) in Meniere’s disease (MD). Methods: Scopus, PubMed, Web of Science, Cochrane Central Register of Control Trials, Google Scholars, Medline, and Embase were systematically searched up to March, 2024. The Preferred Reporting Items for Systematic Reviews and Meta-analyses and Problem/population, intervention, comparison, and outcome (PICO) guidelines were used. Two authors independently reviewed the eligible articles and assessed the quality of them using the Newcastle–Ottawa Scale for case–control studies. Ears diagnosed with MD were considered as affected ears, whereas ears without MD pathology in participants with unilateral MD were considered as unaffected ears. In addition, ears in healthy control groups with both ears without pathology of MD were considered as control ears. A meta-analysis was performed to compare the parameters of WBT between affected, unaffected, and control ears. Results: In total, 5 case–control studies including 446 ears met the inclusion criteria. Among 446 ears, 163, 81, and 202 were affected, unaffected, and control ears, respectively. There were not any statistically significant differences between affected, unaffected, and control ears for mean of resonance frequency (RF) ( P > 0.05). Furthermore, there were not any statistically significant differences between affected, unaffected, and control ears for mean of absorbance. Conclusion: WBT is not sensitive and specific enough to diagnose MD alone. That might be better to use WBT in conjunction with other objective tools, physical examination, and patient’s history instead of relying only on WBT.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.018
metaresearch head score (Gemma)0.039
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.021
Threshold uncertainty score0.096

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0180.039
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0210.039
Bibliometrics0.0080.008
Science and technology studies0.0010.001
Scholarly communication0.0040.002
Open science0.0030.002
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.060
GPT teacher head0.294
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2025
Admission routes1
Has abstractyes

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