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Record W4414575063 · doi:10.21801/ppcrj.2025.112.6

Exploring the Link Between Hepatitis A and B Vaccination and Social Support in the US Population: Insights from the NHANES 2005-2006 Cohort

2025· article· en· W4414575063 on OpenAlexaff
Daniel Bancovsky, Manjushree Shastry, Martina Caccamo, Omar E. Vásquez-Pérez, Merce Avellanet, Kumud Chapagain, Rebecca Santos Soares, Magali Coyoy-Say, Hoàng Bách Nguyễn, Juliana Calit, Asma Qudayr, Cynthia L. P. de Borborema, Sebastine Oiwoh, Jorge Alave, Beatrice Dal Bianco, Maria Antonieta Lopes, Ricardo E. Nunez-Rocha, Maria Magalhaes, Faiez Alsatou, Jessica Rodriguez, Ilgin Genc, Walter Enrique Mogrovejo Ramos, Fabricio Kleber, Patricia Rioja, Ignacio Montealegre, Isabel Cabral, Barbara Grohmann, Y. Wendy Huynh, Lucas Vidoto

Bibliographic record

VenuePrinciples and Practice of Clinical Research Journal · 2025
Typearticle
Languageen
FieldMedicine
TopicHepatitis Viruses Studies and Epidemiology
Canadian institutionsPrincess Margaret Cancer Centre
Fundersnot available
KeywordsVaccinationLogistic regressionSocial supportOddsNational Health and Nutrition Examination SurveyOdds ratioCohortImmunizationHepatitis B vaccine

Abstract

fetched live from OpenAlex

Background: High social support is easily assessed and associated with a healthier lifestyle, including vaccination adherence. Similarly, immunization is a widely available public health statistic associated with healthier behaviors. However, the link between the hepatitis immunization status and social support needs to be explored. Methods: We assessed the association between levels of social support and hepatitis immunization status using the National Health and Nutrition Examination Survey (NHANES), a cross-sectional multidisciplinary database publicly available for researchers. With 2005–2006 data, 2997 participants were included. Statistical analyses were conducted using STATA18.5v software, including the odds ratio of both univariable logistic regression and multivariable logistic regression. After adjusting for clinically relevant confounders, two distinct models were designed: 1) full immunization, and 2) incomplete immunization. Results: Multivariable analysis revealed significantly greater odds of high social support for participants fully or partially immunized against both hepatitis A and B: 3.15 (95% CI 1.03–9.66,p=0.04) and 3.35 (95% CI 1.15–9.75,p=0.03), respectively. Conclusion: Our findings show an association between vaccination and social support in both adjusted models. Individuals not vaccinated at all may behave differently from those willing to be, at least partially, immunized. It seems that a similar behavior that may lead to vaccination may also lead to increased social support. Therefore, our study suggests that hepatitis vaccination could perhaps be a surrogate marker for public-health-related outcomes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.018
metaresearch head score (Gemma)0.031
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.154
Threshold uncertainty score0.977

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0180.031
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.464
GPT teacher head0.533
Teacher spread0.070 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

Explore more

Same venuePrinciples and Practice of Clinical Research JournalSame topicHepatitis Viruses Studies and EpidemiologyFrench-language works237,207