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Record W4414577499 · doi:10.1101/2025.09.24.25336602

Antimicrobial resistance in Ecuador: A One Health situational analysis of governance, infrastructure, and equity gaps

2025· preprint· en· W4414577499 on OpenAlexafffund
Richar Rodríguez‐Hidalgo, Diana Paz, Arne Rückert, Raphael Aguiar, Mayumi Duarte Wakimoto, Phaedra Henley, Mary Wiktorowicz

Bibliographic record

VenuemedRxiv · 2025
Typepreprint
Languageen
FieldImmunology and Microbiology
TopicAntibiotic Use and Resistance
Canadian institutionsYork University
FundersYork UniversityUniversidad Central del Ecuador
KeywordsPublic healthInstitutionalisationEquity (law)Health policyResistance (ecology)Qualitative researchCorporate governanceHealth equityThematic analysis

Abstract

fetched live from OpenAlex

Antimicrobial resistance (AMR) represents a growing global public health threat, undermining therapeutic efficacy and disproportionately affecting vulnerable populations. In Ecuador, the situation is exacerbated by weak surveillance systems and fragmentation among the human, animal, and environmental health sectors. This study analyzes current national approaches that address AMR in Ecuador from a One Health (OH) perspective, with an emphasis on governance, public policy, health infrastructure, and equity. A qualitative approach was employed combining document review, scientific literature analysis, and semi-structured interviews with key informants (KIs) engaged across all OH sectors. Findings reveal structural barriers, including lack of institutionalization of the OH strategy, limited funding for the health system, weak intersectoral coordination, low community awareness, and the absence of equity-oriented policies. In conclusion, the results highlight the urgent need to strengthen the governance of antimicrobial stewardship in Ecuador through strategies that are contextually adapted, aligned with international recommendations, and grounded in a comprehensive multisectoral approach.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.029
Threshold uncertainty score0.059

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0020.003
Science and technology studies0.0010.001
Scholarly communication0.0030.002
Open science0.0010.003
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.283
Teacher spread0.268 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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