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Record W4414603236 · doi:10.1109/jbhi.2025.3614546

A Review of Methods for Trustworthy AI in Medical Imaging: The FUTURE-AI Guidelines

2025· review· en· W4414603236 on OpenAlexaff
Haridimos Kondylakis, Richard Osuala, Xénia Puig-Bosch, Noussair Lazrak, Oliver Díaz, Kaisar Kushibar, Ioanna Chouvarda, Stefanie Charalambous, Martijn P. A. Starmans, Sara Colantonio, Henry C. Woodruff, Zohaib Salahuddin, Gianna Tsakou, Susanna Aussó, L. Cerdá Alberich, Nickolas Papanikolaou, Philippe Lambin, Kostas Marias, Manolis Tsiknakis, Dimitrios I. Fotiadis, Luis Martí‐Bonmatí, Karim Lekadir

Bibliographic record

VenueIEEE Journal of Biomedical and Health Informatics · 2025
Typereview
Languageen
FieldMedicine
TopicArtificial Intelligence in Healthcare and Education
Canadian institutionsArtificial Intelligence in Medicine (Canada)
Fundersnot available
KeywordsGuidelineSet (abstract data type)Domain (mathematical analysis)TrustworthinessMedical imagingHealth careResource (disambiguation)

Abstract

fetched live from OpenAlex

Recent advancements in artificial intelligence (AI) and the vast data generated by modern clinical systems have driven the development of AI solutions in medical imaging, encompassing image reconstruction, segmentation, diagnosis, and treatment planning. Despite these successes and potential, many stakeholders worry about the risks and ethical implications of imaging AI, viewing it as complex, opaque, and challenging to understand, use, and trust in critical clinical applications. The FUTURE-AI guideline for trustworthy AI in healthcare was established based on six guiding principles: Fairness, Universality, Traceability, Usability, Robustness, and Explainability. Through international consensus, a set of recommendations was defined, covering the entire lifecycle of medical AI tools, from design, development, and validation to regulation, deployment, and monitoring. In this paper, we describe how these specific recommendations can be instantiated in the domain of medical imaging, providing an overview of current best practices along with guidelines and concrete metrics on how those recommendations could be met, offering a valuable resource to the international medical imaging community.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.014
metaresearch head score (Gemma)0.003
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.639
Threshold uncertainty score0.995

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0140.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0030.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.319
GPT teacher head0.634
Teacher spread0.315 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2025
Admission routes1
Has abstractyes

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