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Record W4414625974 · doi:10.1510/mmcts.2025.105

Operative management for extent II thoracoabdominal aortoiliac reconstruction for pneumococcal aortitis

2025· article· en· W4414625974 on OpenAlexaff
X S, María Ascaso, Robert Pruna‐Guillen, Marta Hernández‐Meneses, Eduard Quintana

Bibliographic record

VenueMultimedia Manual of Cardio-Thoracic Surgery · 2025
Typearticle
Languageen
FieldMedicine
TopicInfectious Aortic and Vascular Conditions
Canadian institutionsToronto General Hospital
Fundersnot available
KeywordsAortitisContraindicationMycotic aneurysmAortaAortic bifurcationPositron emission tomographyCardiac surgeryAneurysmThoracic aorta

Abstract

fetched live from OpenAlex

Infectious aortitis is an uncommon but life-threatening condition due to its potential to cause mycotic aneurysms, which may lead to vascular rupture. When signs of vascular disruption are present, isolated antibiotic therapy is insufficient, requiring combined open surgical resection of the infected aorta. A 68-year-old woman diagnosed with Streptococcus pneumoniae aortitis is presented. Multiple saccular mycotic aneurysms of varying sizes along the thoracoabdominal aorta, with intense fluorodeoxyglucose uptake on positron emission tomography scan were present in conjunction with extravascular infectious sources. Urgent Crawford extent II thoracoabdominal aortoiliac reconstruction was indicated. Due to extensive atheromatosis of the proximal descending aorta and the relative contraindication to cerebrospinal fluid drainage (spondylodiscitis), repair was performed with profound hypothermia (18°C). Renal protection was achieved using Custodiol and visceral perfusion maintained with cold blood. Each visceral artery was individually reimplanted using a 26mm multibranched graft. Distal reconstruction was completed with a bifurcated prosthesis, given the presence of severe aortic bifurcation calcification. Despite negative intra-operative cultures, histopathology confirmed extensive aortic inflammatory/reparative findings. Post-operative recovery was uneventful. At 1-year follow-up, the patient remains in good condition, with no clinical recurrence, no pathological positron emission tomography/computed tomography uptake, and a stable aortic repair without suppressive antibiotics.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.965
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.350
Teacher spread0.329 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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