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Enhanced Complex Mismatch Negativity and Mnemonic Representations in Older Adult Musicians

2025· preprint· en· W4414641320 on OpenAlexaff
Jennifer A. Bugos, Ricky Chow, Shimin Mo, Shayna R. Rosenbaum, Claude Alain

Bibliographic record

Venuenot available
Typepreprint
Languageen
FieldNeuroscience
TopicNeuroscience and Music Perception
Canadian institutionsBaycrest HospitalUniversity of TorontoYork University
Fundersnot available
KeywordsMnemonicPerceptionMismatch negativityCognitionAuditory perceptionAuditory masking

Abstract

fetched live from OpenAlex

Instrumental music performance is associated with enhanced perceptual processing as evidenced by auditory discrimination and speech-in-noise perception. However, little is known about the extent to which auditory perceptual processes support cognition in aging. We investigated whether music training enhances precision in perception in 26 older amateur and professional musicians (62–85 years, 13 females) and 25 older non-musicians (61–82 years, 16 females). Participants completed a novel paradigm of auditory mnemonic discrimination while electroencephalography (EEG) was recorded. The mismatch negativity (MMN), an event-related potential of change detection, was measured during a passive auditory oddball paradigm with standard and deviant pure-tone sequences differing in pitch contour. Participants subsequently completed an incidental memory test for oddball stimuli (i.e., targets) amongst similar lure sequences (matched for frequency but differing in contour) and dissimilar foil sequences (differing in frequency and contour), as well as a back-to-back perceptual discrimination task. Musicians showed enhanced amplitudes, left-lateralized source activity of the MMN, and increased memory discriminability for targets compared to lures and foils, which was not explained by perceptual discrimination ability or MMN amplitude. No group differences were found for neural or behavioural measures on a mnemonic discrimination task for visual everyday objects. Our results clarify the role of music training on precision in perception and auditory memory in older adult musicians compared to non-musicians. Our findings underscore the contribution of musical engagement to perception and memory to the development of cognitive reserve in aging.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.061
GPT teacher head0.344
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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