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Record W4414710471 · doi:10.1016/j.rehab.2025.102017

Absence from work in the 12 months following mild traumatic brain injury in Europe: a CENTER-TBI cohort study

2025· article· en· W4414710471 on OpenAlexfundno aff
Louis Jacob, Camille Heslot, Nada Anđelić, Olli Tenovuo, Philippe Azouvi

Bibliographic record

VenueAnnals of Physical and Rehabilitation Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicTraumatic Brain Injury Research
Canadian institutionsnot available
FundersDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General HospitalOslo universitetssykehus HFTrnavská univerzita v TrnaveSchool of Health and Related Research, University of SheffieldKepler UniversitätsklinikumMedisinske fakultet, Universitetet i OsloUniversitaire Ziekenhuizen Leuven, KU LeuvenMonash UniversityManchester Biomedical Research CentreDepartment of Neurology, University of PittsburghCentre Hospitalier Universitaire de PoitiersVilnius UniversityBerlin Institute of HealthFundació Institut de Recerca Hospital Universitari Vall d’HebronSzegedi TudományegyetemHelsingin ja Uudenmaan SairaanhoitopiiriTurun Yliopistollinen KeskussairaalaFondazione IRCCS Ca' Granda Ospedale Maggiore PoliclinicoUmeå UniversitetDebreceni EgyetemUniversity of ManitobaUniversiteit AntwerpenAll-India Institute of Medical SciencesRadboud Universitair Medisch CentrumKauno Technologijos UniversitetasCharité – Universitätsmedizin BerlinOdense UniversitetshospitalUniversitätsklinikum HeidelbergAustralian National UniversityOxford Brookes UniversityUniversitair Ziekenhuis AntwerpenUniversity of SheffieldSchool of Medicine, Johns Hopkins UniversityMedizinische Universität WienKarolinska InstitutetUniversity of GlasgowUniversity HospitalsLiverpool Women's NHS Foundation TrustTurun YliopistoNorges Teknisk-Naturvitenskapelige UniversitetHarvard UniversityHaaglanden Medisch CentrumLeids Universitair Medisch CentrumMedizinische Universität InnsbruckFP7 Coordination of Research ActivitiesUniversité de LiègeEuropean CommissionSurgical Reconstruction and Microbiology Research CentrePécsi TudományegyetemMassachusetts General HospitalAzienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino
KeywordsTraumatic brain injuryCohort studyCohortRetrospective cohort studyRehabilitationWork (physics)

Abstract

fetched live from OpenAlex

BACKGROUND: Most of the prior research on absence from work after a mild traumatic brain injury (mTBI) was of a small sample size and had a limited number of follow-up assessments. OBJECTIVES: Therefore, this study investigated the prevalence of absence from work, trajectories, and associated factors in the 12 months following mTBI in Europe. METHODS: Data from a European cohort (CENTER-TBI) were used. Absence from work was assessed at 2 weeks, 3 months, 6 months, and 12 months after mTBI. Associated factors included sociodemographic factors, current psychoactive substance use, pre-injury medical history, injury-related factors, medical care, complications, and discharge, and 2-week follow-up questionnaires. Inferential analyses relied on generalized estimating equations. RESULTS: This study included 1080 adults with mTBI who were working at the time of the injury (median [IQR] age, 46.0 [23.0] years; 69 % men). Absence from work decreased from 32 % at 2 weeks to 20 % at 12 months after the injury (P < 0.001). Around 76 % of adults returned to work within the first 3 months, whereas > 43 % of those absent from work at 3 months remained absent at 12 months. The 3 factors with the strongest association with absence from work were admission to hospital wards (OR = 2.57) or intensive care units (OR = 4.76), the presence of a pre-injury psychiatric disorder (OR = 2.55), and older age (OR = 1.61). CONCLUSIONS: One-fifth of workers with mTBI were absent from work 12 months after the injury. Early identification of those at particular risk for not returning to work should be a clinical priority. STUDY REGISTRATION: NCT02210221 (https://clinicaltrials.gov/).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.026
Threshold uncertainty score0.052

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.002
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.072
GPT teacher head0.411
Teacher spread0.339 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations1
Published2025
Admission routes1
Has abstractyes

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