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Record W4414717476 · doi:10.1016/j.jhsa.2025.07.026

Sensitivity and Specificity of the Brachial Plexus Outcome Measure Activity Scale: A Retrospective Cohort Study

2025· article· en· W4414717476 on OpenAlexafffund
Kate Kyuri Kim, Darcy Fehlings, Karen Lok Yi Wong, Emily S. Ho

Bibliographic record

VenueThe Journal Of Hand Surgery · 2025
Typearticle
Languageen
FieldMedicine
TopicNerve Injury and Rehabilitation
Canadian institutionsHospital for Sick ChildrenHolland Bloorview Kids Rehabilitation HospitalUniversity of Toronto
FundersCanadian Institutes of Health ResearchUniversity of Toronto
KeywordsRetrospective cohort studyBrachial plexusCohort studyMeasure (data warehouse)Outcome (game theory)Sensitivity (control systems)Young adultPsychological intervention

Abstract

fetched live from OpenAlex

PURPOSE: Upper limb impairments occur after incomplete recovery from brachial plexus birth injury (BPBI). Reconstructive surgeries are offered to address specific joint-level impairments; however, complete restoration is not possible. Thus, surgical decisions must carefully consider the goal of improving activity function within the child's life context. The Brachial Plexus Outcome Measure (BPOM) Activity scale is an outcome measure of upper limb activity limitation in children with BPBI. It measures the upper limb function on a 5-point ordinal scale, where a score of ≤3 is theoretically an indicator of surgical candidacy; however, no studies have validated this cutoff score. This study aimed to determine whether the BPOM Activity scale score of ≤3 can accurately identify children with BPBI who may benefit from reconstructive surgery. METHODS: A retrospective cohort study was conducted on children with BPBI (4-18 years). Two independent researchers screened the diagnostic, surgical, and outcome data from the health records and a BPBI database. Sensitivity, specificity, and receiver operating characteristic area under the curve (AUC) of ≤3 scores for shoulder, elbow/forearm, and wrist surgeries were used to identify discriminating ability. These analyses were repeated for all scores (≤1 to ≤5) to determine the best cutoff score. RESULTS: Of the 502 patients screened, 251 were included. The sensitivity and specificity of ≤3 scores had acceptable to excellent discriminating ability for shoulder (90%, 72%, 0.81 AUC), elbow/forearm (89%, 90%, 0.89 AUC), and wrist (80%, 93%, 0.86 AUC) surgeries. Sensitivity, specificity, and AUC were the highest at the ≤3 score compared with other cutoff scores. CONCLUSIONS: The BPOM Activity scale ≤3 cutoff score was able to identify children with BPBI who may benefit from upper limb reconstructive surgery. CLINICAL RELEVANCE: These findings indicate that the BPOM Activity scale can help support shared decision-making for interventions to optimize upper limb function after BPBI.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.006
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.016
Threshold uncertainty score0.211

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0060.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.288
Teacher spread0.268 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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