The importance of regional centres in the management of adults with congenital heart disease in Switzerland: a retrospective, multicentric cohort study
Bibliographic record
Abstract
OBJECTIVE: We aimed to assess the extent of cardiac-related hospitalisations among adult congenital heart disease (ACHD) patients followed at Swiss regional ACHD centres. BACKGROUND: In Switzerland, adult congenital heart disease patients are followed at specialised ACHD centres. According to the Swiss recommendations for standards of adult congenital heart disease care,ACHD centres are categorised as regional and supraregional centres. In contrast to regional centres, supraregional centres require staffing for congenital cardiac surgery and complex congenital cardiac interventions. METHODS: Adult congenital heart disease patients enrolled in the SACHER registry and followed at one of three regional ACHD centres (University Hospital Basel, St Gallen Cantonal Hospital, Lucerne Cantonal Hospital) from May 2014 to March 2022 were included. Data were abstracted by chart review and included demographics, clinical and surgical history, follow-up duration and cardiac-related hospitalisations during follow-up. RESULTS: In total, 1031 patients (accounting for 22% of patients from the entire SACHER cohort) were included (570 at University Hospital Basel, 231 at St Gallen Cantonal Hospital, 230 at Lucerne Cantonal Hospital). During a median (IQR) follow-up of 3 (1-5) years, there were 237 hospitalisations (100 [42%] emergencies) among 136 (13%) patients. The majority of admissions (157, 66%), occurred at the regional centre. Arrhythmias (49 of 64 admissions, 77%) and heart failure hospitalisations (26 of 34, 76%) were mainly managed locally. The main reasons for referral to supraregional ACHD centres were heart surgery (32/56, 57%) and complex structural percutaneous interventions (pulmonary valve replacement [3/3, 100%] and balloon dilation of aortic coarctation [7/7, 100%]). CONCLUSION: In Switzerland, regional ACHD centres provide an important contribution to the management of the growing cohort of adult congenital heart disease patients. Most hospitalisations were managed locally. This was particularly true for emergencies, arrhythmia and heart failure hospitalisations. The main reasons for referral to supraregional ACHD centres were complex percutaneous interventions.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".