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Record W4414889297 · doi:10.1016/j.pmedr.2025.103250

Stressful life events, perceived degree of stress, and the risk of lung cancer

2025· article· en· W4414889297 on OpenAlexafffundabout
Saeedeh Moayedi-Nia, Hartley Dutczak, Lesley Richardson, Jack Siemiatycki, Anita Koushik

Bibliographic record

VenuePreventive Medicine Reports · 2025
Typearticle
Languageen
FieldMedicine
TopicCancer survivorship and care
Canadian institutionsMcGill UniversityUniversité de Montréal
FundersInstitute of Cancer ResearchFonds de Recherche du Québec - SantéCanadian Institutes of Health ResearchUniversité de MontréalMedical Research Council CanadaMcGill University
KeywordsPsychosocialLung cancerDegree (music)Stress (linguistics)Psychological stressRisk perceptionQuality of life (healthcare)Cancer

Abstract

fetched live from OpenAlex

Objective: We examined the experience of acute stressful life events and their perceived impact in relation to lung cancer incidence. Methods: In a population based case-control study in Montreal, Canada, 1061 cases and 1422 controls (recruited 1996-2001) were queried on their experience of loss events (death of a family member, divorce/separation) and socioeconomic events (job loss, major income reduction, or a move to a new city) in the prior 6 years, and their own perceived stressfulness (impact) of the event. Using multivariable unconditional logistic regression, we estimated odds ratios (ORs) and 95 % confidence intervals (CIs) of lung cancer associated with experiencing at least one of the five individual events ("any stressful event"), "any loss event" and "any socioeconomic event", and their impact. Results: Experiencing "any stressful life event" in the previous 6 years was not associated with lung cancer, even when accounting for perceived impact. When considering event type, loss events suggestively increased lung cancer odds, particularly when perceived as high impact (OR = 1.84, 95 % CI: 0.97-3.49). Socioeconomic events did not increase lung cancer odds. Conclusion: This study of recent stressful life events and their perceived impact contributes to knowledge on the possible role of psychosocial stress in lung cancer.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.044
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.306
Teacher spread0.292 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes3
Has abstractyes

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