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Record W4414965819 · doi:10.56093/675qc250

Polycystic kidney disease in a Labrador dog

2025· article· en· W4414965819 on OpenAlexaboutno aff
S. Sivaraj

Bibliographic record

VenueIndian Journal of Veterinary Pathology · 2025
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic and Kidney Cyst Diseases
Canadian institutionsnot available
Fundersnot available
KeywordsTrichromePolycystic kidney diseaseKidneyMasson's trichrome stainPolycystic diseaseFibrosisAutosomal Recessive Polycystic Kidney DiseaseUrinalysisHistopathology

Abstract

fetched live from OpenAlex

An eleven-month labrador dog was brought to Veterinary clinical complex, Veterinary College and Research Institute, Namakkal with a history of anorexia, frequent vomition and progressive weight loss. Hematology and serum biochemical analysis showed severe anaemia, leukopaenia, azotemia, hyperphosphatemia and hypocalcemia. The case was tentatively diagnosed as Polycystic kidney disease based on clinical signs, haematobiochemical parameters and ultrasonography. In spite of the palliative treatment, the animal died within a week and the same was referred to Department of Veterinary Pathology for necropsy. The carcass was severely emaciated and ulcers were noticed in the oral cavity. Kidneys showed numerous, whitish, irregular and varying-sized fluid-filled cysts studded over the entire renal parenchyma. Histopathological examination of the kidney revealed large amount of fibrous tissue in the interstitium with irregularly dilated cysts and some cysts with homogeneous, acidophilic material in the lumen. On Masson’s trichrome staining and Van Gieson’s staining, the fibrous stroma appeared blue and bright red in colour respectively. The liver showed portal fibrosis with bile duct hyperplasia. This communication deals with the pathology of congenital polycystic kidney disease in a dog.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0020.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0020.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.274
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes1
Has abstractyes

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