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Record W4414972556 · doi:10.3389/fmed.2025.1641767

Determinants of complementary and integrative medicine use in inflammatory bowel disease: a focus on probiotics, prebiotics, and fermentable dietary fibres

2025· article· en· W4414972556 on OpenAlexaffabout
Ammar Hassanzadeh Keshteli, Richa Chibbar, Melissa Silva, Karen Danois, Rosica Valcheva, Eytan Wine, Levinus A. Dieleman

Bibliographic record

VenueFrontiers in Medicine · 2025
Typearticle
Languageen
FieldMedicine
TopicGastrointestinal motility and disorders
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsIntegrative medicineModalitiesInflammatory bowel diseaseAlternative medicineFocus (optics)Health careIrritable bowel syndromeInflammatory Bowel Diseases

Abstract

fetched live from OpenAlex

Background: Complementary and integrative medicine (CIM) modalities, particularly probiotics, prebiotics, and fermentable dietary fibers (PPF) use in IBD patients is common and increasing, particularly for symptom management. This study aimed to assess the prevalence of CIM and PPF use among IBD patients and to identify potential demographic and clinical factors associated with utilization. Methods: This was a cross-sectional study of adult IBD patients at a tertiary IBD centre in Western Canada. A self-administered questionnaire and chart review were performed, focusing on demographic and clinical characteristics, CIM and PPF use in the past year (current) and/or lifetime, and sources of awareness about PPF products. Results: A total of 267 patients were included, 182 with CD and 85 with UC. Overall, 89.9% of participants reported CIM use in the current year, while the current and lifetime prevalence of PPF use was 51 and 63%, respectively. UC diagnosis was associated with increased likelihood of current PPF use (OR: 1.91, 95% CI: 1.10-3.12). Holding a university degree was associated with increased likelihood of lifetime PPF use (OR: 2.21, 95% CI: 1.07-4.55). PPF awareness through gastroenterologists (OR: 3.19, 95% CI: 1.55-6.58) was significantly associated with lifetime PPF use. Conclusion: Use of CIM modalities such as PPF is common among IBD patients. This study found that lifetime PPF use was associated with higher level of education and awareness through gastroenterologists. Healthcare providers, and specifically gastroenterology specialists, should routinely inquire about PPF use and educate IBD patients. Further studies are required to determine the benefit derived from these products.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.032
Threshold uncertainty score0.064

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.283
Teacher spread0.266 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes2
Has abstractyes

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