A meta-analysis of efficacy and safety of parietal pleurectomy versus pleural abrasion in treating spontaneous pneumothorax
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Bibliographic record
Abstract
BACKGROUND: Spontaneous pneumothorax is a common benign disease. Its treatment aims to restore the collapsed lungs, relieve symptoms, and prevent recurrence. Currently, video-assisted thoracoscopic bullectomy combined with parietal pleural fixation has become the mainstream treatment method. However, the choice between parietal pleurectomy and pleural abrasion remains a subject of continuous debate. Consequently, we conducted a meta-analysis to assess the differences in perioperative efficacy and complications between the two surgical methods combined with bullectomy. METHODS: Relevant literatures were searched in PubMed, Web of Science, Embase and The Cochrane Library from the establishment date of each database to February 1, 2025. According to the inclusion and exclusion criteria, the literatures were screened. The meta-analysis was conducted using Review Manager 5.3 and Stata 16MP software. The Cochrane Collaboration’s tool for assessing the risk of bias and the Newcastle-Ottawa Scale were employed to evaluate the quality of the included studies. RESULTS: A total of 15 literatures were included, involving 2732 patients. The meta-analysis results showed that the postoperative pain degree of the two groups was similar [MD = 0.32, 95%CI (−0.13 ~ 0.77), P = 0.17]. However, the pleural abrasion group had shorter operation time [MD = 15.87, 95%CI (11.30 ~ 20.44), P < 0.0001], less intraoperative blood loss [MD = 14.62, 95%CI (8.58 ~ 20.66), P < 0.0001], less total postoperative drainage volume [MD = 67.82, 95%CI (10.26 ~ 125.38), P=0.02], shorter postoperative drainage time [MD = 0.38, 95%CI (0.05 ~ 0.72), P༝0.02], and shorter hospital stay [MD = 0.25, 95%CI (0.04 ~ 0.46), P༝0.02] compared with the parietal pleurectomy group, and the differences were statistically significant. In terms of safety, the parietal pleurectomy group would increase the incidence of postoperative hemorrhage [OR = 3.99, 95%CI (1.49 ~ 10.65), P = 0.006], but there was no statistically significant difference in the incidence of postoperative atelectasis (P = 0.47), pulmonary leakage (P = 0.95) and pulmonary infection (P = 0.05). In addition, the parietal pleurectomy group could effectively reduce the long-term recurrence rate of patients [OR = 0.56, 95%CI (0.41 ~ 0.77), P = 0.0003], and the difference was statistically significant. CONCLUSIONS: For patients with spontaneous pneumothorax and bullae, parietal pleurectomy inevitably increases the perioperative burden and prolongs the hospital stay of patients, but can effectively prevent postoperative recurrence. The two surgical methods have similar safety, but parietal pleurectomy will increase the risk of postoperative hemorrhage. Clinically, the optimal treatment plan should be selected based on the individual characteristics of patients.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.008 | 0.004 |
| Bibliometrics | 0.001 | 0.002 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it