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Record W4415031759 · doi:10.1002/lio2.70280

Extracorporeal Septoplasty for Severe Nasal Septal Deviation: A Systematic Review

2025· review· en· W4415031759 on OpenAlexaboutno aff
Matteo Lazzeroni, Jérôme R. Lechien, Mario Lentini, Pasquale Capaccio, Alberto Maria Saibene, Michele Gaffuri, Antonio Mario Bulfamante, Luca Giovanni Locatello, Portelli Tancredi, I Tozzi di Angelo, Federico Sireci, Antonino Maniaci

Bibliographic record

VenueLaryngoscope Investigative Otolaryngology · 2025
Typereview
Languageen
FieldMedicine
TopicNasal Surgery and Airway Studies
Canadian institutionsnot available
Fundersnot available
KeywordsSeptoplastyExtracorporealNasal septumExtracorporeal circulationMEDLINE

Abstract

fetched live from OpenAlex

Objective: Extracorporeal septoplasty (ECS) is a surgical technique used to address severe nasal septal deviations, especially in patients in whom in situ septoplasty (ISS) is insufficient. This systematic review assesses the efficacy, safety, and clinical outcomes of ECS techniques, including conventional and modified ECS methods. Data Sources: PRISMA-compliant systematic search of PubMed, Scopus, Web of Science, and Embase. Methods: Studies on ECS techniques were included. Eligibility criteria were established using the PICOTS framework. Study quality was assessed using the Cochrane Risk of Bias 2 tool and the Newcastle-Ottawa Scale. Functional and aesthetic improvements were primary outcomes, while complication rates represented secondary outcomes. Results: Twenty-two studies (retrospective, prospective, and RCTs) met the inclusion criteria. ECS was associated with significant functional improvement, as assessed by nasal obstruction scores measured by NOSE scores, acoustic rhinometry, and rhinomanometry. Aesthetic results were also satisfactory, with a significant improvement in the nasofrontal angle, nasolabial angle, and the tip projection index, as well as good patients' satisfaction. Complications were rare, with few cases of septal perforation, graft resorption, or residual nasal obstructive symptoms. Evidence strength was limited considering the majority of included studies were retrospective, with inherent bias risks, small sample sizes, and inconsistent follow-up durations. Conclusions: ECS may be a successful and safe method for severe septal deviation correction, providing functional and aesthetic results with a low complication rate. More high-quality, multicenter RCTs with long-term follow-up will be required for a standardization of surgical protocols and outcome measures. Level of Evidence: 2.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesMeta-epidemiology (narrow)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.362
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.005
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0110.003
Bibliometrics0.0010.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.046
GPT teacher head0.352
Teacher spread0.307 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designSystematic review
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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