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Record W4415075284 · doi:10.1111/aor.70018

The Orthotic Effect of Functional Electrical Stimulation on Reactive Stepping for People With Incomplete Spinal Cord Injury

2025· article· en· W4415075284 on OpenAlexafffund
Matthew G. Heffernan, Jonguk Lee, Katherine Chan, Elizabeth L. Inness, Kei Masani, Kristin E. Musselman

Bibliographic record

VenueArtificial Organs · 2025
Typearticle
Languageen
FieldMedicine
TopicSpinal Cord Injury Research
Canadian institutionsToronto Rehabilitation InstituteUniversity of Toronto
FundersToronto Rehabilitation InstituteCanada Research ChairsCraig H. Neilsen Foundation
KeywordsFunctional electrical stimulationSpinal cord injuryStimulationSpinal cord stimulationSpinal cordElectric stimulation

Abstract

fetched live from OpenAlex

BACKGROUND: Individuals with incomplete spinal cord injury (iSCI) often face challenges initiating reactive steps, leading to an increased risk of falls. Reactive balance training (RBT) can improve balance control; however, it is difficult to participate in RBT without the ability to initiate a reactive step independently. Functional electrical stimulation (FES) has been used to facilitate participation in RBT. FES applied to the common fibular nerve (CFN) following iSCI initiates a flexor withdrawal response, promoting rapid hip and knee flexion and ankle dorsiflexion, potentially aiding the execution of reactive stepping responses. This cross-sectional study aimed to evaluate the orthotic (i.e., immediate) effect of FES on reactive stepping parameters in participants with chronic, motor iSCI. METHODS: Sixteen individuals with chronic motor iSCI completed the Lean-and-Release test, which elicits reactive stepping through a simulated forward fall. Participants completed 10-20 trials, with FES applied in half at random. The behavioral response (i.e., single-step, two-step, ≥ 3-step, or fall) of each trial was recorded. Temporal parameters (i.e., foot-off time, swing time, and stepping time) and spatial parameters (i.e., length, height, and width) of the first reactive step were also recorded. RESULTS: The proportion of single-step (p = 0.31), two-step (p = 0.19), ≥ 3-step (p = 0.44) and fall (p = 0.42) behavioral responses did not differ between FES and No-FES conditions. Additionally, the temporal (foot-off time (p = 0.43), swing time (p = 0.80), and step time (p = 0.95)) and spatial parameters (length (p = 0.73), height (p = 0.70), and width (p = 0.54)) of the first reactive step did not differ between conditions. CONCLUSIONS: FES had no orthotic effect on reactive stepping parameters in individuals with chronic motor iSCI.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.572
Threshold uncertainty score0.339

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.380
Teacher spread0.343 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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