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Record W4415093807 · doi:10.1016/j.tipsro.2025.100349

Operational assessment of tattooless breast radiotherapy using AlignRT surface guidance

2025· article· en· W4415093807 on OpenAlexafffund
A. Malhotra, Andrew K. H. Robertson, Ian Sun, Samantha A. M. Lloyd

Bibliographic record

VenueTechnical Innovations & Patient Support in Radiation Oncology · 2025
Typearticle
Languageen
FieldPhysics and Astronomy
TopicAdvanced Radiotherapy Techniques
Canadian institutionsUniversity of British Columbia
FundersBC Cancer Foundation
KeywordsRadiation therapyBrachytherapyImage-guided radiation therapyMEDLINEQuality assurance

Abstract

fetched live from OpenAlex

Background and purpose: Surface guided radiation therapy (SGRT) is a new approach for patient setup that can replace tattoo-based positioning. The permanent body markings that come with this long-standing standard of care can have a lasting negative emotional impact on cancer survivors. This study evaluates surface guidance as an alternative positioning modality, comparing speed, accuracy, and cost of the two techniques. Methods: Setup time and positional accuracy prior to radiographic localization for patients receiving radiation therapy for breast cancer were compared between two linear accelerators, one with and one without surface guidance technology. A Wilcoxon rank sum test was used to determine statistically significant differences in setup time and positional shifts. Cost projections per fraction and per patient for both modalities were conducted. Results: SGRT positional accuracy and setup time were equivalent to or better than tattoo-based setup. SGRT setup was faster for all photon treatments by 11 s. Deep inspiration breath hold setup times were equivalent for both positioning modalities, but SGRT was faster by 23 s for free breathing setups. There were no statistically significant differences in the magnitude of positional shifts on pre-treatment imaging. SGRT costs are broken down into item costs and staffing costs, with final estimates dependent on a center's capacity for treatments per day. Conclusions: Surface guided patient positioning for breast radiotherapy is fiscally feasible and non-inferior to permanent tattoos in terms of set up time and accuracy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.612
Threshold uncertainty score0.864

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.390
Teacher spread0.373 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2025
Admission routes2
Has abstractyes

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