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Record W4415133221 · doi:10.1093/pnasnexus/pgaf289

New methods on the block: Taxonomic identification of archaeological bones in resin-embedded sediments through paleoproteomics

2025· article· en· W4415133221 on OpenAlexaff
Zandra Fagernäs, Gaudry Troché, Paul Goldberg, Jean‐Jacques Hublin, Shannon P. McPherron, William Chase Murphree, Jesper V. Olsen, Dennis Sandgathe, Nikolay Sirakov, Marie Soressi, Tsenka Tsanova, Alain Turq, Michael Wierer, Frido Welker, Vera Aldeias

Bibliographic record

VenuePNAS Nexus · 2025
Typearticle
Languageen
FieldSocial Sciences
TopicPleistocene-Era Hominins and Archaeology
Canadian institutionsSimon Fraser University
FundersNational Science Foundation of Sri LankaEuropean Research CouncilNovo Nordisk FondenLeakey FoundationMax-Planck-Institut für Evolutionäre AnthropologieBulgarian Academy of SciencesNovo NordiskMax-Planck-GesellschaftMinistère de la CultureEuropean CommissionUniversity of PennsylvaniaHORIZON EUROPE Framework ProgrammeNederlandse Organisatie voor Wetenschappelijk OnderzoekNational Science Foundation
KeywordsTaxonContext (archaeology)PleistoceneIdentification (biology)ChronologyTaxonomic rankTaphonomy

Abstract

fetched live from OpenAlex

Abstract The integration of biomolecular studies of past organisms with geoarchaeological studies can significantly improve our understanding of the relative chronology and context of archaeologically (in)visible behaviors. However, the complexity and sedimentological heterogeneity of archaeological deposits at a microscopic scale is often not taken into consideration in biomolecular studies. Here, we investigate the preservation and retrieval of paleoproteomic data from bone fragments embedded in Pleistocene resin-impregnated sediment blocks. We show that resin impregnation has minimal effect on skeletal protein taxonomic identifications in modern skeletal material but observe an increase in oxidation of methionines. We then successfully retrieve proteins from resin-impregnated blocks from the Paleolithic sites of Bacho Kiro Cave, La Ferrassie, and Quinçay. The taxonomic identifications of minute bones encased in resin are in line with previous analyses of the faunal communities of these sites, with a diversity of taxa (Bos sp./Bison sp., Equus sp., Ursus sp., and Caprinae) observed at a microscale in Bacho Kiro. This differs from results from La Ferrassie where most of the samples are identified as a single taxon (Bos sp./Bison sp.) across different areas of the site. The block from Quinçay only provided taxonomic identification of two out of eleven bone-derived samples, likely due to diagenesis. Our work indicates that paleoproteomes can be retrieved from bone fragments at a microstratigraphic resolution, enabling the detailed study of faunal community composition at a scale that more closely matches that of past human occupations.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.390
Threshold uncertainty score0.360

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.051
GPT teacher head0.379
Teacher spread0.328 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2025
Admission routes1
Has abstractyes

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