Effectiveness of the Cooled Radiofrequency Ablation of Genicular Nerves in Patients with Chronic Knee Pain
Bibliographic record
Abstract
Background: Multiple modalities are existing for chronic knee pain management. Genicular nerve neurolysis/Rhyzotomy and intra-articular steroid injection (IASI) are available treatment options for patients with knee osteoarthritis. There is increasing evidence supporting the effectiveness of cooled radiofrequency ablation (RFA) in treating genicular nerves for patients with chronic knee osteoarthritis (OA). This study aims to compare the efficacy of cooled RFA with that of intra-articular steroid injection (IASI) in patients with knee pain caused by OA. Aims and Objectives: The primary objective of this observational, prospective study was to evaluate the longterm outcomes, including pain, function, and perceived effect of treatment, in subjects undergoing cooled radiofrequency ablation (CRFA) who have pain due to osteoarthritis (OA) of the knee. Methods: The prospective observational type of study was carried out on thirty patients with Kellgren–Lawrence grade 2–4 knee OA in the department of Anaesthesiology at Gandhi Medical College Bhopal after the approval of Institutional Ethics Committee of our hospital. The patients were assigned into 2 groups randomly as IASI (N=15) and CRFA (N=15) group. All the patients were evaluated with Visual analogue score (VAS) for pain intensity and Western Ontario and Mc Master Universities Osteoarthritis Index (WOMAC) for functional status of the patients. All assessments were measured and compared at baseline, 1 month, 3 month and 6th month after treatment. Furthermore, patient satisfaction was also recorded. Results: All evaluation parameters were significantly improved in IASI and CRFA groups. Both VAS and WOMAC score of CRFA group were significantly lower than VAS and WOMAC score of IASI group during all the intervals of time (p<0.001). Satisfaction grades did not differ between the two groups. Conclusions: Cooled radiofrequency ablation (CRFA) of the genicular nerve and intra-articular steroid injection (IASI) are potential treatments for knee joint pain in osteoarthritis. However, CRFA provides better pain relief and enhances functional capacity in patients with knee joint pain from osteoarthritis compared to IASI.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".